Results 41 to 50 of about 4,346,862 (230)

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Vital Pulp Therapy for Permanent Molars

, 2016
Guidelines for vital molar therapy are presented based on best available evidence. Often the cause for vital intervention is due to caries, but seldom the depth of the carious lesion is mentioned in literature, which may hamper the evaluation of ...
Bjørndal, Lars
core   +1 more source

Arrayed Magnetic Accelerator Synergistically Enhances Orthodontic Tooth Movement via Microtubule Assembly‐Mediated Periodontal Remodeling

Advanced Science, EarlyView.
Mechanical orthodontic treatment for malocclusion is limited by slow remodeling and risks due to poor biomechanical sensing. This study shows that static magnetic fields (SMFs) enhance mechanical sensation in periodontal ligament cells, promoting inflammation and osteoclast activity.
Yiling Lou, Jiwei Sun, Peng Chen, Caihong Mao, Junyuan Zhang, Haoqi Lei, Xiaoqing Han, Yaxuan Zhang, Yuheng Jiang, Yulin Jia, Bin Su, Lili Chen   +11 more
wiley   +1 more source

Multifunctional Ph-Responsive Nanozymes For Vital Pulp Therapy

International Dental Journal
Aim or purpose: This study develops pH-responsive nanozymes to overcome impaired pulp repair in caries-induced pulpitis by sequentially eliminating bacterial infection through enzymatic cascades, modulating inflammatory responses, and promoting hDPSC ...
Yingli Li, Yingli Li, Wenting He, Xinyi Liu, Mengyu Jiao   +4 more
doaj   +1 more source

Reln mRNA Delivery Drives Neurogenic Bone Regeneration by Orchestrating Schwann Cell‐Mediated Exosomal Trafficking

Advanced Science, EarlyView.
MSNs serve as a robust vehicle for CRISPRa‐mediated Reln induction, driving bone repair through the establishment of a neurogenic‐supportive microenvironment. ABSTRACT Neurogenic bone regeneration is essential for the effective restoration of bone tissue functionality, while the mechanisms and new strategies underlying neurogenic bone regeneration ...
Shuai Lin, Qianwen Li, Duo Liu, Mingzhao Li, Han Zhang, Liujing Chen, Yan Yu, Jiuhui Jiang, Chun Xu, Ruili Yang   +9 more
wiley   +1 more source

Demystifying pulpotomy in adult dentition: Case reports

Эндодонтия Today
Vital pulp therapy for a carious exposure in a mature permanent tooth may be a reasonable alternative to root canal therapy or extraction. Mineral Trioxide Aggregate (MTA) or Biodentine are bioactive materials which are alternatives to traditionally used
H. Desai, S. Mulay, S. Shetty, A. Tandale   +3 more
doaj   +1 more source

A Justification for the Trend Towards Indirect Pulp Therapy [PDF]

, 2015
Purpose: The purpose of this retrospective chart review was to determine how primary molars needing vital pulp therapy have been treated in the past four years at Virginia Commonwealth University (VCU) and to determine which treatments: indirect pulp ...
Kuhnen, Marissa
core   +1 more source

Localized Hydrogen Release Driven by Mg–Pd Microgalvanic Cells from 3D‐Printed Microneedles Reverses Redox Homeostasis for Psoriasis Treatment

Advanced Science, EarlyView.
A 3D printing microneedle (MP‐MN), loading magnesium‐based micro‐galvanic cells (MP), is designed for improving psoriasis. H2 generated from MP‐MN scavenges ROS and •OH, actives NRF2‐KEAP1 pathway, and decreases inflammation, thereby effectively restoring the oxidative stress homeostasis of psoriatic skin and suppressing the excessive proliferation of ...
Xinyue Shao, Zongyan He, Ning Yang, Lixuan Yin, Xujie Sun, Jingtong Qi, Xiaolong Feng, Yihui Zhang, Yiran Liu, Zhengwei Huang, Tianqun Lang   +10 more
wiley   +1 more source

Cytotoxicity and Bioactivity of Five Hydraulic Silicate Cements in Human Dental Pulp Cells at Different Setting Stages

International Dental Journal
Introduction and aims: Evidence regarding the biological responses of human dental pulp cells (hDPCs) to freshly mixed hydraulic silicate cements remains limited.
Chanakarn Sinsareekul, Suphalak Phothichailert, Ravipha Suwittayarak, Vorapat Trachoo, Chatvadee Kornsuthisopon, Waleerat Sukarawan, Yoshio Yahata, Thanaphum Osathanon, Sirawut Hiran-us   +8 more
doaj   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source