Results 41 to 50 of about 11,515 (279)

The scientific management of deep carious lesions in vital teeth using contemporary materials—a narrative review

Frontiers in Dental Medicine, 2022
AimThe aim of this article is to review the scientific evidence for deep caries removal in permanent vital teeth and the choice of dentine replacement material and restoration of the teeth to maintain long-term tooth vitality and function.MethodThe two ...
M. Al-Ali, M. Al-Ali, J. Camilleri
doaj   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Demystifying pulpotomy in adult dentition: Case reports

Эндодонтия Today
Vital pulp therapy for a carious exposure in a mature permanent tooth may be a reasonable alternative to root canal therapy or extraction. Mineral Trioxide Aggregate (MTA) or Biodentine are bioactive materials which are alternatives to traditionally used
H. Desai, S. Mulay, S. Shetty, A. Tandale   +3 more
doaj   +1 more source

Cell therapy comparison of dental pulp stem cells, hepatocytes, and their exosomes for liver fibrosis treatment in rats

Animal Models and Experimental Medicine, EarlyView.
DPSCs, hepatocytes, and exosomes were tested for liver fibrosis therapy. Exosome‐based treatment exhibited superior antioxidative and regenerative effects. Liver enzymes, oxidative stress, and profibrotic markers were significantly reduced. α‐SMA, desmin, and related gene expression were downregulated.
Sahar Rahimi, Seyedeh Mahdieh Khoshnazar, Ali Derakhshani, Nader Shahrokhi   +3 more
wiley   +1 more source

Histopathological evaluation of root canal filling materials for primary teeth [PDF]

, 2010
This study aimed to assess the response of apical and periapical tissues of dogs¿ teeth after root canal filling with different materials. Forty roots from dogs¿ premolars were prepared biomechanically and assigned to 4 groups filled with: Group I ...
Leonardo, Mário Roberto, Nelson Filho, Paulo, Gatón Hernández, Patrícia, Silva, Léa Assed Bezerra da, Queiroz, Alexandra Mussolino de, Oliveira, Daniela S. B. de, Silva, Raquel Assed Bezerra da, HERNÁNDEZ, Patrícia Gatón, NELSON-FILHO, Paulo   +8 more
core   +1 more source

Vital Pulp Therapy

, 2022
The human dental pulp is a type of connective tissue found within the hard tissues (dentine and enamel) of the teeth. The vitality of dental pulp is essential for long-term tooth survival. The dental pulp is at risk of infection when exposed to damage such as caries or tooth fracture, which can lead to pain, necrosis, and infection of the jaw bone and ...
openaire   +1 more source

Dose‐dependent pathogenicity and inflammatory imbalance in severely immunodeficient mice infected with mpox virus

Animal Models and Experimental Medicine, EarlyView.
This study establishes an NPG (NOD.Cg‐Prkdcscid Il2rgtm1/Vst) mouse model for severe monkeypox virus infection in immunocompromised hosts, demonstrating dose‐dependent disease severity and revealing that unbalanced pro‐inflammatory cytokine release drives pathogenesis, providing insights for therapeutic interventions. Abstract The global spread of mpox
Na Li, Ziqing Jia, Zhe Cong, Jianrong Ma, Jiahan Lu, Yongzhi Hou, Fei Wang, Jiasen Yang, Ting Chen, Jingjing Zhang, Dong Zhang, Jing Xue   +11 more
wiley   +1 more source

Five-Year Success of Endodontics Plus Vital Pulp Therapy in a Symptomatic Maxillary Molar: A Case Report. [PDF]

Clin Case Rep
ABSTRACT This case report details the integration of nonsurgical endodontic treatment (NSET) and vital pulp therapy (VPT) for symptomatic irreversible pulpitis (SIP) and symptomatic apical periodontitis (SAP) in a mature maxillary molar, with 5‐year follow‐up.
Al-Nahlawi T, Assadian H, Ghorvei Nossrat Z.   +2 more
europepmc   +2 more sources

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

BMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang   +9 more
wiley   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source