Results 151 to 160 of about 431,721 (352)

Benefícios dos Ativadores Seletivos dos Recetores de Vitamina D em Doentes Transplantados Renais [PDF]

open access: yes, 2015
Severe chronic kidney disease may lead to disturbances, such as hyperphosphatemia, increased secretion of fibroblast growth factor -23 (FGF -23) and vitamin D deficiency.
Aires, I   +9 more
core  

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

open access: yesAdvanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian   +5 more
wiley   +1 more source

Vitamin A Deficiency Alters the Phototransduction Machinery and Distinct Non-Vision-Specific Pathways in the Drosophila Eye Proteome [PDF]

open access: gold, 2022
Mukesh Kumar   +12 more
openalex   +1 more source

Vitamin B12 deficiency common in primary hypothyroidism [PDF]

open access: yes, 2008
OBJECTIVE: To assess the prevalence and clinical features of B12 deficiency in hypothyroid patients and to evaluate clinical response in symptoms to B12 replacement therapy.
Akhter, J.   +7 more
core   +1 more source

Dual Targeting of Tau Kinases and Autophagy by Abemaciclib Independent of CDK4/6 Inhibition

open access: yesAdvanced Science, EarlyView.
Abemaciclib rescues cognitive function and attenuates tau pathology in Alzheimer's disease models, but not through its known cancer‐fighting mechanism. This study demonstrates that abemaciclib operates independently of CDK4/6 inhibition, instead directly targeting tau kinases CaMKII and GSK3β while simultaneously promoting autophagic clearance of ...
Jihui Han   +9 more
wiley   +1 more source

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

open access: yesAdvanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang   +7 more
wiley   +1 more source

Awareness of Vitamin D Deficiency among the General Population in Taif City, Saudi Arabia [PDF]

open access: diamond, 2023
Ali Ghithan AlGarni   +7 more
openalex   +1 more source

ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling

open access: yesAdvanced Science, EarlyView.
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao   +19 more
wiley   +1 more source

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