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Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer. [PDF]

open access: yesPLoS ONE, 2016
Normal or high serum vitamin B-12 levels can sometimes be seen in a B-12 deficient state, and can therefore be misleading. High levels of Methymalonic Acid (MMA) and Homocysteine (HC) have been identified as better indicators of B-12 deficiency than the ...
Pankaj Vashi   +4 more
doaj   +2 more sources

Study of Vitamin B 12 deficiency and peripheral neuropathy in metformin-treated early Type 2 diabetes mellitus

open access: diamondIndian Journal of Endocrinology and Metabolism, 2016
Background: Long-term therapy with metformin was shown to decrease the Vitamin B 12 level and manifested as peripheral neuropathy. Aim: The aim of this study is to define the prevalence of Vitamin B 12 deficiency in early Type 2 diabetic patients ...
Rudra Prasad Roy   +7 more
doaj   +2 more sources

Clinical Manifestations of Vitamin B-12 Deficiency [PDF]

open access: bronzeAMA Journal of Ethics, 2006
An overview of the biochemical and physiological functions of vitamin B-12 and the symptoms of vitamin B-12 deficiency. Virtual Mentor is a monthly bioethics journal published by the American Medical Association.
Jennifer Reenan
openaire   +3 more sources

Prevalence of vitamin B12 deficiency and its associated neuropathy in patients taking long term metformin therapy in Type 2 diabetes mellitus

open access: yesJournal of Applied Pharmaceutical Research, 2023
Background: Diabetic people on metformin are more likely to develop vitamin B12 deficiency. There has been little research into the duration of therapy and dose of metformin that causes B12 deficiency and peripheral neuropathy.
Suresh Kumar   +5 more
doaj   +1 more source

VITAMIN B 12 DEFICIENCY MIMICKING THROMBOTIC MICROANGIOPATHY: A CASE REPORT

open access: yesHematology, Transfusion and Cell Therapy, 2022
Objective: Vitamin B12 has an important role in DNA synthesis, erythrocyte development and neurological functions by the transfer of one-carbon methyl groups.
Müzeyyen Aslaner Ak   +3 more
doaj   +1 more source

Vitamin B12 deficiency and Parkinson’s disease

open access: yesНеврология, нейропсихиатрия, психосоматика, 2023
Parkinson’s disease (PD) is a progressive neurodegenerative disease with various clinical manifestations, its origin not always can be explained only by dopamine deficiency. Long-term treatment with levodopa (especially its intraduodenal administration),
Z. A. Zalyalova, E. V. Ekusheva
doaj   +1 more source

Plasma Vitamin B-12 Levels and Risk of Alzheimer’s Disease: A Case-Control Study

open access: yesGerontology and Geriatric Medicine, 2022
Introduction: Vitamin B-12 deficiency is a frequent condition in the elderly population. High homocysteine levels, which can contribute to arterial damage and blood clots in blood vessels, usually indicate a deficiency in vitamin B-12.
Lochana Shrestha MD   +4 more
doaj   +1 more source

Involvement of Spermidine in the Reduced Lifespan of Caenorhabditis elegans During Vitamin B12 Deficiency

open access: yesMetabolites, 2019
Vitamin B12 deficiency leads to various symptoms such as neuropathy, growth retardation, and infertility. Vitamin B12 functions as a coenzyme for two enzymes involved in amino acid metabolisms.
Tomohiro Bito   +6 more
doaj   +1 more source

A study of clinical profile of vitamin B 12 deficiency with special reference to dermatologic manifestations in a Tertiary Care Hospital in sub-Himalayan Bengal

open access: yesIndian Journal of Dermatology, 2015
Background: Vitamin B 12 deficiency is thought to be uncommon in the eastern parts of India including Bengal and the eastern states as compared to the northern and southern parts of India.
Kaushik Sen   +3 more
doaj   +1 more source

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