Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer. [PDF]
PLoS One, 2016 Normal or high serum vitamin B-12 levels can sometimes be seen in a B-12 deficient state, and can therefore be misleading. High levels of Methymalonic Acid (MMA) and Homocysteine (HC) have been identified as better indicators of B-12 deficiency than the ...
Vashi P +4 more
europepmc +3 more sources
Proton Pump Inhibitors, H2-Receptor Antagonists, Metformin, and Vitamin B-12 Deficiency: Clinical Implications. [PDF]
Adv Nutr, 2018 There is clear evidence that proton-pump inhibitors (PPIs), H2-receptor antagonists (H2RAs), and metformin can reduce serum vitamin B-12 concentrations by inhibiting the absorption of the vitamin.
Miller JW.
europepmc +2 more sources
Sub-optimal vitamin B-12 levels among ART-naïve HIV-positive individuals in an urban cohort in Uganda. [PDF]
PLoS ONE, 2012 Malnutrition is common among HIV-infected individuals and is often accompanied by low serum levels of micronutrients. Vitamin B-12 deficiency has been associated with various factors including faster HIV disease progression and CD4 depletion in resource ...
Aggrey S Semeere +5 more
doaj +8 more sources
Prevalence of vitamin B 12 deficiency and associated factors among primary school children: North East Ethiopia: multicenter cross-sectional study. [PDF]
J Health Popul NutrBackground The prevalence of Vitamin B12 deficiency is common and is more frequent in low- and middle-income countries with a poor or inadequate diet of animal foods. In Ethiopia, researches related to the status of micronutrients in children are limited.
Melaku EE +5 more
europepmc +2 more sources
How common is vitamin B-12 deficiency? [PDF]
The American Journal of Clinical Nutrition, 2009 In considering the vitamin B-12 fortification of flour, it is important to know who is at risk of vitamin B-12 deficiency and whether those individuals would benefit from flour fortification. This article reviews current knowledge of the prevalence and causes of vitamin B-12 deficiency and considers whether fortification would improve the status of ...
L. Allen
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Optic neuropathy as a presenting feature of vitamin B-12 deficiency: A systematic review of literature and a case report. [PDF]
Ann Med Surg (Lond), 2020 Ata F +7 more
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Diagnosing vitamin B-12 deficiency on the basis of serum B-12 assay [PDF]
BMJ, 2006 Serum vitamin B-12 concentrations are measured to assess the presence of its deficiency in patients presenting with haematolological, neurological, and neuropsychiatric abnormalities. Replacement therapy is instituted promptly, particularly to prevent irreversible neurological and cognitive dysfunction.
V. Devalia
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Vitamin B-12 deficiency in the elderly: current dilemmas [PDF]
The American Journal of Clinical Nutrition, 1997 Vitamin B-12 deficiency is present in up to 15% of the elderly population as documented by elevated methylmalonic acid with or without elevated total homocysteine concentrations in combination with low or low-normal vitamin B-12 concentrations. Clinical signs and symptoms of vitamin B-12 deficiency are insensitive in elderly subjects and comorbidity in
S P, Stabler, J, Lindenbaum, R H, Allen
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The Human Serum Metabolome of Vitamin B-12 Deficiency and Repletion, and Associations with Neurological Function in Elderly Adults. [PDF]
J Nutr, 2017 Brito A +13 more
europepmc +2 more sources
Folate Deficiency Is Prevalent in Women of Childbearing Age in Belize and Is Negatively Affected by Coexisting Vitamin B-12 Deficiency: Belize National Micronutrient Survey 2011. [PDF]
J Nutr, 2017 Rosenthal J +10 more
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