Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer. [PDF]
PLoS ONE, 2016 Normal or high serum vitamin B-12 levels can sometimes be seen in a B-12 deficient state, and can therefore be misleading. High levels of Methymalonic Acid (MMA) and Homocysteine (HC) have been identified as better indicators of B-12 deficiency than the ...
Pankaj Vashi +4 more
doaj +3 more sources
Proton Pump Inhibitors, H2-Receptor Antagonists, Metformin, and Vitamin B-12 Deficiency: Clinical Implications. [PDF]
Adv Nutr, 2018 There is clear evidence that proton-pump inhibitors (PPIs), H2-receptor antagonists (H2RAs), and metformin can reduce serum vitamin B-12 concentrations by inhibiting the absorption of the vitamin.
Miller JW.
europepmc +2 more sources
Sub-optimal vitamin B-12 levels among ART-naïve HIV-positive individuals in an urban cohort in Uganda. [PDF]
PLoS ONE, 2012 Malnutrition is common among HIV-infected individuals and is often accompanied by low serum levels of micronutrients. Vitamin B-12 deficiency has been associated with various factors including faster HIV disease progression and CD4 depletion in resource ...
Aggrey S Semeere +5 more
doaj +17 more sources
The Human Serum Metabolome of Vitamin B-12 Deficiency and Repletion, and Associations with Neurological Function in Elderly Adults. [PDF]
J Nutr, 2017 Background: The specific metabolomic perturbations that occur in vitamin B-12 deficiency, and their associations with neurological function, are not well characterized.Objective: We sought to characterize the human serum metabolome in subclinical vitamin
Brito A +13 more
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How common is vitamin B-12 deficiency? [PDF]
The American Journal of Clinical Nutrition, 2009 In considering the vitamin B-12 fortification of flour, it is important to know who is at risk of vitamin B-12 deficiency and whether those individuals would benefit from flour fortification. This article reviews current knowledge of the prevalence and causes of vitamin B-12 deficiency and considers whether fortification would improve the status of ...
L. Allen
openaire +4 more sources
Folate Deficiency Is Prevalent in Women of Childbearing Age in Belize and Is Negatively Affected by Coexisting Vitamin B-12 Deficiency: Belize National Micronutrient Survey 2011. [PDF]
J Nutr, 2017 Background: Folate deficiency, vitamin B-12 deficiency, and anemia can have adverse effects on birth outcomes. Also, low vitamin B-12 reduces the formation of metabolically active folate.Objectives: We sought to establish the baseline prevalence of and ...
Rosenthal J +10 more
europepmc +2 more sources
Vitamin B-12 deficiency in the elderly: current dilemmas [PDF]
The American Journal of Clinical Nutrition, 1997 Vitamin B-12 deficiency is present in up to 15% of the elderly population as documented by elevated methylmalonic acid with or without elevated total homocysteine concentrations in combination with low or low-normal vitamin B-12 concentrations. Clinical signs and symptoms of vitamin B-12 deficiency are insensitive in elderly subjects and comorbidity in
Sally P. Stabler +2 more
openaire +4 more sources
Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency: randomised placebo controlled trial [PDF]
British medical journal, 2010 Objectives To study the effects of metformin on the incidence of vitamin B-12 deficiency (
J. de Jager +8 more
semanticscholar +5 more sources
Optic neuropathy as a presenting feature of vitamin B-12 deficiency: A systematic review of literature and a case report. [PDF]
Ann Med Surg (Lond), 2020 Ata F +7 more
europepmc +2 more sources
Indian Journal of Dermatology, 2015 Background: Vitamin B 12 deficiency is thought to be uncommon in the eastern parts of India including Bengal and the eastern states as compared to the northern and southern parts of India.
Kaushik Sen +3 more
doaj +2 more sources