Results 261 to 270 of about 948,114 (320)
ChemBioChem, Accepted Article.Glutathione (GSH), a tripeptide essential for maintaining redox balance in the human body, plays a critical role in protecting cells from oxidative stress. A deficiency in GSH is linked to increased oxidative damage and the progression of various disorders, including cancer and neurological diseases.
Francesca Milano +6 more
wiley +1 more source
Vitamin B<sub>12</sub> deficiency - another challenge to expand newborn laboratory screening? [PDF]
Samuel Stanovský +14 more
openalex +1 more source
Steerable Delivery Sheath for Optimized LAA Closure: First Experience and Procedural Outcomes
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Background The new Amplatzer Steerable Delivery Sheath is a delivery system designed to improve ease‐of‐use and procedural results of left atrial appendage closure (LAAC). We aimed to compare procedural results after switching our LAAC program at a tertiary care center with the Amulet device to the Steerable Delivery Sheath, with a control ...
Matthias Mezger +4 more
wiley +1 more source
Catheterization and Cardiovascular Interventions, EarlyView.ABSTRACT Patients undergoing transcatheter aortic valve implantation (TAVI) often require long‐term oral anticoagulation (OAC), but it is unclear whether to continue or interrupt OAC during the procedure. This meta‐analysis compares clinical outcomes of continuing versus interrupting OAC during TAVI.
Jefferson Manoel Borges Martins +9 more
wiley +1 more source
Lipophilic Resazurin in Bioelectrochemical Systems: Role in Regulating Carbon Metabolic Pathways
ChemElectroChem, EarlyView.This study clarifies the mechanism by which lipophilic shuttles regulate carbon metabolism in Shewanella. Lipophilic electron shuttles, such as resazurin, permeate into the periplasm to mediate extracellular electron transfer, thereby altering the redox potential sensed by inner‐membrane quinones and consequently activating the NADH‐dependent metabolic
Siyu Tan +8 more
wiley +1 more source
ChemMedChem, Accepted Article.The cannabinoid receptor type 2 (CB2R) is overexpressed under pathological conditions. PET is a suitable non‐invasive imaging technique for diagnosing disease states, but requires a radiotracer that binds to CB2R with high affinity and selectivity. Currently, there is no suitable candidate routinely used in the clinics.
Lea Ueberham +4 more
wiley +1 more source
Manganese Neurotoxicity and Familial Disorders of Manganese Transport
Annals of the Child Neurology Society, EarlyView.ABSTRACT Manganese is the 12th most common element in the Earth's crust and is an essential industrial component. Biologically, this metal plays an important role as a constituent of numerous enzymes. While manganese is required for normal biochemical and physiological processes, manganese excess can lead to significant toxicity, particularly to the ...
Sidney M. Gospe Jr.
wiley +1 more source
ChemPlusChem, EarlyView.The article evaluates polyoxometalate–ionic liquids (POM–ILs) as biocidal agents against lampenflora in the UNESCO‐listed Pommery Champagne cellar. POM–ILs effectively inhibit microbial colonization over one year with minimal visual impact and outperform the commercial biocide Preventol RI80.
Stéphanie Eyssautier‐Chuine +10 more
wiley +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Pemetrexed is a cornerstone in chemo(immunotherapy) of non‐small cell lung cancer and mesothelioma; however, it is contraindicated in patients with renal impairment due to severe toxicity concerns. Therefore, a large proportion of patients is withheld from effective chemo(immunotherapy).
Nikki de Rouw +18 more
wiley +1 more source