Results 161 to 170 of about 950,377 (309)

The Emerging Parkinson's Disease Oxylipin‐Ome

Advanced Science, EarlyView.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

Vitamin B-6 Deficiency Induces Anxiety-Like Behavior in Sprague-Dawley Rats by Disrupting Gut Homeostasis. [PDF]

J Nutr
Amarasena S, Hossain KS, Rasouli A, Bertolo RF, Yuan Q, Mayengbam S.   +5 more
europepmc   +1 more source

Effects of vitamin B-6 supplementation on oxidative stress and inflammatory response in neonatal rats receiving hyperoxia therapy. [PDF]

J Food Drug Anal, 2018
Lee MS, Su TC, Huang YC, Yang RC, Kao JK, Lee CH, Tseng JJ, Hsu CS, Hsu CL.   +8 more
europepmc   +1 more source

Self‐Amplifying Redox Cycle Triggers Ferroptosis/Cuproptosis Synergy for Enhanced Bacterial Eradication

Advanced Science, EarlyView.
This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao, Shaolong Qiu, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +6 more
wiley   +1 more source

Vitamin B-6, Independent of Homocysteine, Is a Significant Factor in Relation to Inflammatory Responses for Chronic Kidney Disease and Hemodialysis Patients. [PDF]

Biomed Res Int, 2017
Chen CH, Yeh EL, Chen CC, Huang SC, Huang YC.   +4 more
europepmc   +1 more source

Microbial Odorant Detection Guides Drosophila Parasitoids Seeking Hosts in Fermenting Fruits

Advanced Science, EarlyView.
Yeast microbes in fermenting fruits attract both host flies and their parasitoid wasps. Female Leptopilina boulardi detect yeast‐emitted ethyl esters via two olfactory receptors, LbouOR167 and LbouOR136. A conserved residue, Leu159, is critical for binding these compounds, enabling female wasps to locate host‐rich habitats.
Yueqi Lu, Lan Pang, Wenqi Shi, Ting Feng, Zhi Dong, Yifeng Sheng, Sicong Zhou, Longtao Yu, Hao Guo, Ying Wang, Jiani Chen, Jianhua Huang   +11 more
wiley   +1 more source

Chitosan‐Carbon Dot Composite Materials Form a Leaf Surface Barrier to Mitigate the Enrichment and Invasion of Nanoplastics: From Leaf Interface to Systemic Response

Advanced Science, EarlyView.
Foliar spraying of CS‐CDs can form a film on the leaves of Brassica rapa, effectively reducing the enrichment and absorption of PS in the leaves, while increasing the biomass and nutrient content of the plants. In addition, CS‐CDs can also enrich the interfoliar microbial community and activate the plant's own defense metabolic pathways.
Beibei Zhao, Mei Li, Mengjiao Fan, Chuanhuan Liu, Jie Jiang, Jia Song, Yingzhu Liu   +6 more
wiley   +1 more source

Kynurenine pathway metabolites: relevant to vitamin B-6 deficiency and beyond. [PDF]

Am J Clin Nutr, 2013
Ciorba MA.
europepmc   +1 more source

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK). [PDF]

Am J Clin Nutr, 2018
Zuo H, Tell GS, Ueland PM, Nygård O, Vollset SE, Midttun Ø, Meyer K, Ulvik A.   +7 more
europepmc   +1 more source