Results 121 to 130 of about 331,878 (359)

Safety and Effectiveness of Stoss Therapy in Children with Vitamin D Deficiency [PDF]

, 2020
Objectives: Paediatric vitamin D (25-hydroxyvitamin D - 25OHD) deficiency can lead to nutritional rickets and extra-skeletal complications. Compliance with daily therapy can be difficult, making high dose, short-term vitamin D (stoss) therapy attractive ...
Tannous, Paul
core   +1 more source

Climate Change Threatens Micronutrient Density of European Winter Wheat

Advanced Science, EarlyView.
Micronutrients are vital for human health. Wheat is a major staple crop and a significant source of minerals and B‐vitamins. The impact of climate change on their content remains largely unknown. We evaluated micronutrient levels in European winter wheat grown under historical and projected climate conditions. Our findings indicate that future climates
Da Cao, Jennifer Michel, Eline Lorer, Markus Weinmann, Jacques Le Gouis, Claire Léon, Sibille Perrochon, David Alvarez, Vincent Leemans, Iñaki Balanzategui Guijarro, Jordi Moya Laraño, Sara Sánchez Moreno, Symanczik Sarah, Waibel Matthias, Hervé Vanderschuren, Cécile Thonar, Pierre Delaplace, Dominique Van Der Straeten   +17 more
wiley   +1 more source

Vitamin D in combination with menopausal hormonal therapy in women. [PDF]

РМЖ. Мать и дитя
D.K. Muradova1, A.E. Esedova2, F.S. Mamedov2, T.S. Magomedova2 1LLC Center for Medicine and Diagnostics "My Doctor", Makhachkala, Russian Federation 2Dagestan State Medical University, Makhachkala, Russian Federation Background: A multitude ...
D.K. Muradova, A.E. Esedova, F.S. Mamedov, T.S. Magomedova   +3 more
doaj  

Improved Systemic Immunochemotherapy Employing an Oxaliplatin‐TLR7/8 Agonist Prodrug Strategy

Advanced Science, EarlyView.
A platinum(IV) prodrug is developed to systemically deliver the TLR7/8 agonist gardiquimod. Tumor‐targeting is mediated by an albumin‐binding maleimide, which limits premature complex activation. Ox‐Gardi‐Mal accumulates specifically in the tumor, where it activates the immune system.
Michael Gutmann, Martijn Dijkstra, Philipp Salomon, Jamie Cowles, Anja Federa, Dina Baier, Carola Jaunecker, Iemima Semerean, Venla Karvonen, Christine Pirker, Maria Sibilia, Dietmar Herndler‐Brandstetter, Petra Heffeter, Bernhard K. Keppler, Christian R. Kowol, Walter Berger   +15 more
wiley   +1 more source

A 50-year-old female with dysuria, dysporia, numbness and weakness of extremities

Chinese Journal of Contemporary Neurology and Neurosurgery, 2015
This paper reports one patient, with a history of autoimmune gastritis, who presented dysuria and dysporia for 5 years, weakness of left upper limb for one and a half years, and numbness and weakness of extremities for 2 months.
Lin PENG, Wei-hai XU, Bin PENG, Li-ying CUI   +3 more
doaj  

Vitamin B₆deficiency experimentally-induced bone and joint disorder: microscopic, radiographic and biochemical evidence [PDF]

, 1994
Priscille G. Massé, Kenneth P. H. Pritzker, Maria Gabriela Araújo Mendes, Adele L. Boskey, H. Weiser   +4 more
openalex   +1 more source

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source

Subacute combined degeneration of the spinal cord due to vitamin B₁₂ deficiency [PDF]

, 2011
Jon Fenton, Sanjeev Rajakulendran, R. H. Chinn, J. C. Janssen   +3 more
openalex   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

Ocular manifestations of vitamin B-complex deficiency. [PDF]

, 1967
G Venkataswamy
openalex   +1 more source