Results 11 to 20 of about 331,878 (359)

S-adenosylmethionine and superoxide dismutase 1 synergistically counteract Alzheimer's disease features progression in tgCRND8 mice [PDF]

, 2017
Recent evidence emphasizes the role of dysregulated one-carbon metabolism in Alzheimer's Disease (AD). Exploiting a nutritional B-vitamin deficiency paradigm, we have previously shown that PSEN1 and BACE1 activity is modulated by one-carbon metabolism ...
Cavallaro, Rosaria A, Fiorenza, Maria Teresa, Fuso, Andrea, Nicolia, Vincenzina, Scarpa, Sigfrido   +4 more
core   +2 more sources

A study of clinical profile of vitamin B 12 deficiency with special reference to dermatologic manifestations in a Tertiary Care Hospital in sub-Himalayan Bengal

Indian Journal of Dermatology, 2015
Background: Vitamin B 12 deficiency is thought to be uncommon in the eastern parts of India including Bengal and the eastern states as compared to the northern and southern parts of India.
Kaushik Sen, Pradyot Sinhamahapatra, Joseph Lalhmachhuana, Subhabrata Ray   +3 more
doaj   +1 more source

Maternal vitamin deficiency mimicking multiple acyl-CoA dehydrogenase deficiency on newborn screening

Molecular Genetics and Metabolism Reports, 2021
Background: In infancy multiple acyl-CoA dehydrogenase deficiency (MADD) is commonly a severe inherited metabolic disease caused by genetic defects in electron transfer flavoprotein (ETF) or ETF ubiquinone oxidoreductase.
Gwendolyn Gramer, Georg F. Hoffmann, Julia B. Hennermann   +2 more
doaj   +1 more source

Effects of vitamin B-12 supplementation on neurologic and cognitive function in older people: a randomized controlled trial. [PDF]

, 2015
BACKGROUND: Moderate vitamin B-12 deficiency is relatively common in older people. However, there is little robust evidence on the effect of vitamin B-12 supplementation on neurologic and cognitive outcomes in later life.
Alan D Dangour, Astrid E Fletcher, Balk, Carmel, Chou, Clarke, Cox, Dangour, de Jager, Delis, Diana Elbourne, Elizabeth Allen, Eussen, Fine, Fine, Folstein, Ford, Goldberg, Goodglass, Hin, Hunt, Institute of Medicine, Jernerén, Ken Whyte, Kerry Mills, Kimura, Leishear, Leishear, Lindenbaum, Louise Letley, Mann, Marcus Richards, Mills, Mills, O'Leary, Podsiadlo, Ricardo Uauy, Robert Clarke, Smith, Stabler, Sucharita, Sucharita, Tombaugh, Tombaugh, Turgut, Vellas, Watanabe, Yetley   +47 more
core   +1 more source

The Role of Vitamin D in Kidney Transplantation Outcomes: A Systematic Review

Life, 2022
The aim of this systematic review is to assess the impact of vitamin D on the outcomes of kidney transplantation and investigate whether its deficiency is associated with a negative impact.
Georgios Koimtzis, Leandros Stefanopoulos, Verity Brooker, Georgios Geropoulos, Christopher G. Chalklin, Sapna Gupta, Eliot Carrington-Windo, Maria Papaioannou, Theodosios S. Papavramidis   +8 more
doaj   +1 more source

Special considerations for vitamin D in the South Asian population in the UK [PDF]

, 2017
The human requirement for vitamin D is achieved primarily through the synthesis of this pre-hormone in the skin during exposure to UVB radiation, with only a minor contribution from the diet year-round.
Bhojani, Issak, Lowe, Nicola M
core   +1 more source

Vitamin D and Disease Severity in Multiple Sclerosis-Baseline Data From the Randomized Controlled Trial (EVIDIMS) [PDF]

, 2020
Objective: To investigate the associations between hypovitaminosis D and disease activity in a cohort of relapsing remitting multiple sclerosis (RRMS) and clinically isolated syndrome (CIS) patients.
Bellmann-Strobl, Judith, Brandt, Alexander Ulrich, Bäcker-Koduah, Priscilla, Dörr, Jan, Paul, Friedemann, Scheel, Michael, Wernecke, Klaus-Dieter, Wuerfel, Jens   +7 more
core   +2 more sources

Effects of Mild and Severe Vitamin B Deficiencies on the Meiotic Maturation of Mice Oocytes

Nutrition and Metabolic Insights, 2017
We investigated the effects of vitamin B 1 deficiency on the meiosis maturation of oocytes. Female Crl:CD1 (ICR) mice were fed a 20% casein diet (control group) or a vitamin B 1 –free diet (test group).
Ai Tsuji, Toshinobu Nakamura, Katsumi Shibata   +2 more
doaj   +1 more source

Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer. [PDF]

PLoS ONE, 2016
Normal or high serum vitamin B-12 levels can sometimes be seen in a B-12 deficient state, and can therefore be misleading. High levels of Methymalonic Acid (MMA) and Homocysteine (HC) have been identified as better indicators of B-12 deficiency than the ...
Pankaj Vashi, Persis Edwin, Brenten Popiel, Carolyn Lammersfeld, Digant Gupta   +4 more
doaj   +1 more source

Multiple sclerosis-like neurological manifestations in a coeliac patient: nothing is as it seems [PDF]

, 2012
Cobalamin (vitamin B(12)) deficiency occurs with several disorders, involving different organs and systems, including blood, bowel, nervous system and eyes.
CARROCCIO, Antonio, D'ALCAMO, Alberto, DI STEFANO, Laura, MANSUETO, Pasquale   +3 more
core   +1 more source