Results 121 to 130 of about 14,153,510 (299)

The Role of Vitamin D and Vitamin D Receptor in Sepsis

Current Issues in Molecular Biology
Sepsis acts as the leading cause of mortality in intensive care units, characterized by life-threatening organ dysfunction due to a dysregulated host response to infection. Vitamin D (VD) pleiotropic functions were demonstrated in different biological processes, including inflammation and immunity.
Shenglan Shang, Dongxin Chen, Yuqi Wei, Shuo Zou, Qiuyue Chang, Hong Zhou, Airong Yu   +6 more
openaire   +3 more sources

Vitamin D Metabolism and Guidelines for Vitamin D Supplementation

Clinical Biochemist Reviews, 2020
Vitamin D is essential for bone health and is known to be involved in immunomodulation and cell proliferation. Vitamin D status remains a significant health issue worldwide. However, there has been no clear consensus on vitamin D deficiency and its measurement in serum, and clinical practice of vitamin D deficiency treatment remains inconsistent.
openaire   +3 more sources

Vitamin D and vitamin D receptor levels in children with attention-deficit/hyperactivity disorder

, 2018
Nilfer Sahin,1 Hatice Altun,2 Ergül Belge Kurutas,3 Damla Balkan1 1Department of Child and Adolescent Psychiatry, Muğla Sıtkı Koçman University, Muğla, Turkey; 2Department of Child and Adolescent Psychiatry, Kahramanmaras Sutcu Imam ...
Altun H, Kurutas EB, Balkan D, Sahin N
core  

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

Rhodiola rosea Rhizome Extract-Mediated Green Synthesis of Silver Nanoparticles and Evaluation of Their Potential Antioxidant and Catalytic Reduction Activities

ACS Omega, 2021
Daihua Hu, Xu Yang, Wang Chen, Zili Feng, Chingyuan Hu, Fei Yan, Xiaohua Chen, Dong Qu, Zhiyuan Chen   +8 more
doaj   +1 more source

Advances in Vitamin D encapsulation: from lipid formulations to polymeric nanoparticles

Frontiers in Soft Matter
Vitamin D deficiency has emerged as a global public health concern, with implications spanning skeletal disorders, cardiovascular diseases, immune dysfunction, and cancer.
Eleni Axioti, Iolanda Francolini, Vincenzo Taresco, Robert J. Cavanagh   +3 more
doaj   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

Advanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang, Yuchuan Chen, Jiayuan Wan, Jianzheng Yang, Lijian Chen, Qingyuan Li, Anding Zhou, Nian Zhou, Jiuyang Ding, Qi Wang, Jian Sun   +10 more
wiley   +1 more source

Vitamin D Supplementation During Pregnancy and Maternal and Neonatal Vitamin D Status at ≤32 Weeks Gestation: Romanian Prospective Observational Cohort Study

Children
Background: Recently, vitamin D deficiency (VDD) has been described as a pandemic, affecting all groups of the population. Pregnant women and preterm infants are particularly vulnerable to vitamin D deficiency.
Ioana Andrada Radu, Manuela Cucerea, Cristian Gheonea, Radu Chicea, Dumitru Alin Teacoe, Bianca Ioana Mutică, Samuel Bogdan Todor, Gabriela Boța, Dragoș Popescu, Bianca Cosmina Coțovanu, Maria Livia Ognean   +10 more
doaj   +1 more source

A Molecular Engineering Strategy to Fine‐Tune Phototoxicity of AIE Probes for Super‐Resolution Imaging of Mitochondrial Cristae Dynamics

Advanced Science, EarlyView.
Regulation of molecular packing, phototoxicity, and ROS output of AIE photosensitizers is achieved through carboxylation and alkyl‐chain‐length tuning. The probe designed via this strategy enables super‐resolution visualization of inner‐mitochondrial‐membrane cristae dynamics under controlled oxidative stress, and fluorescence‐lifetime imaging of ...
Kongqi Chen, Mengjie Wang, Chuen Kam, Zhiming Wang, Qinrong Zhang, Sijie Chen   +5 more
wiley   +1 more source