Results 331 to 340 of about 16,728,945 (382)

Enhanced Selenium Supplement Extends Lifespan and Delays Multi‐Organs Aging by Regulating the Sik1 Pathway Through Maintaining Calcium Homeostasis

open access: yesAdvanced Science, EarlyView.
Aging involves physiological decline and heightened disease susceptibility, necessitating effective interventions. Redox‐responsive selenium‐loaded nanoparticles (SeMSNs) are developed, which delay cellular senescence by reducing oxidative stress and senescence markers (p16/p21). In aged mice, SeMSNs extend lifespan, improve organ function, and restore
Yang Yu   +15 more
wiley   +1 more source

Dysregulated vitamin D signaling in Hashimoto's thyroiditis: an integrated transcriptomic study in a Korean cohort. [PDF]

open access: yesFront Endocrinol (Lausanne)
Lim DW   +7 more
europepmc   +1 more source

Bimetallic Nanozyme Amplifier for Synergistic Ferroptosis‐Cuproptosis and Metabolic Reprogramming to Reshape Immunosuppressive Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
The Bimetallic Nanozyme Amplifier (PEG@AuCZ@CC) to maximize hydrogen peroxide production and reprogram tumor metabolism from glycolysis to oxidative phosphorylation. This shift enhances ferroptotic/cuproptotic signaling cascades and creates a glucose‐enriched but lactate‐depleted tumor microenvironment (TME), effectively overcoming immune tolerance in ...
Jianzhang Luo   +9 more
wiley   +1 more source

Interconversions between RNS Revealed by Transient Voltammetry with Porphyrin‐Modified Carbon Nanopipettes in Single Living Cells

open access: yesAdvanced Science, EarlyView.
By using porphyrin modified conductive nanopipettes, transient voltammetry can be directly applied to reveal the dynamic and complex electrochemical reactions between the reactive nitrogen species inside the single living cells. Abstract Reactive nitrogen species (RNS) play crucial roles in cellular signaling, but their quantification is very ...
Hongli Cao   +5 more
wiley   +1 more source

Hot‐Pressing Annealing‐Induced Light Utilization Enhancement and Crystallinity Optimization Enable High‐Performance Narrowband Ultraviolet Photodetectors for Real‐Time Ultraviolet Radiation Monitors

open access: yesAdvanced Science, EarlyView.
By utilizing a hot‐pressing (HP) annealing strategy, Cs3Cu2I5 films with larger grains vertically spanning the entire thickness are fabricated. Because HP annealing enhances light utilization and charge transport in Cs3Cu2I5/GaN heterojunction, the HP device achieves superior detection performance while maintaining narrowband photoresponse to UVA/UVB ...
Jingli Ma   +13 more
wiley   +1 more source

Selective Lithium Recovery via Stepwise Transition Metal Crystallization in a Natural Deep Eutectic Solvent

open access: yesAdvanced Science, EarlyView.
A biodegradable, natural deep eutectic solvent (DES) is designed for preferential lithium (Li) leaching from various cathodes under mild conditions (60 °C, 8 h). Compared to traditional acids and DESs, it achieves >96% Li leaching from black mass with minimal transition metal dissolution via a stepwise reduction, complexation, hydrolysis, and ...
Jingxiu Wang   +8 more
wiley   +1 more source

The Role of Vitamin D in Diabetes Ketosis and Ketoacidosis. [PDF]

open access: yesChronic Dis Transl Med
Zhang C   +4 more
europepmc   +1 more source

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