Results 151 to 160 of about 77,458 (359)

Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase

Advanced Science, EarlyView.
Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song, Yu Wei, Peng Jia, Shan He, Qian Wang, Manman Xu, Hongzhi Liu, Pengtao Bao, Shanyue Guan, Xiaozhong Qu   +9 more
wiley   +1 more source

VITAMIN D LEVELS IN MULTIPLE SCLEROSIS

Malang Neurology Journal, 2019
Background : Multiple Sclerosis is a  neurologic  disease that effect  Central Nervous System(CNS).  Vitamin D is a liposoluble prohormone. It is thought that vitamin D deficiency is responsible for Lots of diseases which includes MS .
Zeynep Hulya Durmaz, D. Ayan, A. Demir, H. Demir   +3 more
semanticscholar   +1 more source

Targeted Medical Therapies for Vascular Anomalies: A Clinical Review

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Vascular anomalies represent a broad spectrum of disorders characterized by aberrant blood or lymphatic vessel development, which can lead to complex clinical phenotypes. Historically, vascular anomalies were classified solely on the basis of their clinical and histopathologic features.
Whitney Eng
wiley   +1 more source

Vitamin D in amyotrophic lateral sclerosis.

Functional Neurology, 2017
Vitamin D supplementation has been proposed as a potential treatment to delay amyotrophic lateral sclerosis (ALS) progression. The aims of this study were to compare retrospectively vitamin D blood levels in ALS patients with those in healthy subjects ...
L. Libonati, E. Onesti, M. Gori, M. Ceccanti, C. Cambieri, A. Fabbri, V. Frasca, Maurizio Inghilleri   +7 more
semanticscholar   +1 more source

Epstein–Barr Virus, Lower Vitamin D, Low Sun Exposure, and HLA‐DRB1*1501 Risk Variant Share Common Epigenetic Pathways Leading to Multiple Sclerosis Onset

Annals of Neurology, EarlyView.
Objectives Multiple sclerosis (MS) onset risk factors include Epstein–Barr virus (EBV) indices (including host response), lower serum 25‐vitamin D (25(OH)D) levels, low sun exposure, and HLA‐DRB1*1501. The underlying molecular mechanisms are unclear. Here, we examined mediation through differential DNA methylation (DNAm) to better understand possible ...
Steve Simpson‐Yap, Ellen Morwitch, Samuel A. Tanner, Sarah M. Thomson, Alex Eisner, Rod A. Lea, Trevor J. Kilpatrick, Jeannette Lechner‐Scott, Rodney J. Scott, Alexandre Xavier, Vicki E. Maltby, Robyn M. Lucas, Bruce V. Taylor, Brett A. Lidbury, Simon A. Broadley, Ingrid van der Mei, Mehari Woldemariam Merid, Boris Novakovic, Richard Saffery, Anna Karin Hedström, Pernilla Stridh, Tomas Olsson, Maja Jagodic, Lars Alfredsson, Anne‐Louise Ponsonby, for the Ausimmune Investigator Group, Caron Chapman, Alan Coulthard, Keith Dear, Terry Dwyer, Trevor Kilpatrick, Robyn Lucas, Tony McMichael, Anne‐Louise Ponsonby, Bruce Taylor, Patricia Valery, Ingrid van der Mei, David Williams   +37 more
wiley   +1 more source

The Epidemiology of Primary Lateral Sclerosis: Results from a Population‐Based Cohort

Annals of Neurology, EarlyView.
Objective In this population‐based study, we described the epidemiology of primary lateral sclerosis (PLS) in northern Italy and compared the clinical characteristics of patients with PLS to those with predominant upper motor neuron (PUMN) involvement and classic amyotrophic lateral sclerosis (ALS).
Rosario Vasta, Enrico Matteoni, Giorgio Pellegrino, Antonio Canosa, Umberto Manera, Francesca Palumbo, Maurizio Grassano, Sara Cabras, Alessandra Maccabeo, Fabrizio D'Ovidio, Gabriele Mora, Salvatore Gallone, Elisa D'Angelo, Letizia Mazzini, Fabiola De Marchi, Cristina Moglia, Adriano Chiò, Andrea Calvo   +17 more
wiley   +1 more source

IS THERE A LINK BETWEEN A LOW LEVEL OF VITAMIN D AND MULTIPLE SCLEROSIS?

Romanian Journal of Neurology, 2015
Multiple Sclerosis is a neurological disorder consisting in autoimmune and inflammatory manifestations. Its evolution is characterized by axonal demyelination among the central nervous system.
D. Popescu, Dan Trofin, O. Bolbocean, B. Ignat, Dan Trofin   +4 more
semanticscholar   +1 more source

Vitamin D Deficiency as a Factor Associated with Cognitive Impairment in Patients with Type 2 Diabetes Mellitus

Siriraj Medical Journal
Objective: Vitamin D as an essential nutrient is increasingly being studied and reported to have roles in diabetes and cognitive function through its antioxidant, anti-inflammatory, and neuroprotective functions.
Valentina Tjandra Dewi, Anak Agung Ayu Putri Laksmidewi, Anak Agung Ayu Suryapraba, Wira Gotera, I Putu Eka Widyadharma, I Made Oka Adnyana   +5 more
doaj  

Nonspecific pain is a marker for hypovitaminosis D in patients undergoing evaluation for sleep disorders: a pilot study

Nature and Science of Sleep, 2013
David E McCarty,1 Aronkumar Reddy,1 Quinton Keigley,2 Paul Y Kim,1 Stephen Cohen,2 Andrew A Marino1 1Division of Sleep Medicine, Department of Neurology, Louisiana State University Health Sciences Center, 2School of Medicine, Louisiana State University ...
McCarty DE, Reddy A, Keigley Q, Kim PY, Cohen S, Marino AA   +5 more
doaj  

Serum Otoconin-90 and Otolin-1 Concentrations in Benign Paroxysmal Positional Vertigo

Biomolecules
Objective: The aim was to evaluate the value of otolith-associated protein otoconin-90 (OC90) and otolin-1 in the pathogenesis research and clinical treatment of benign paroxysmal positional vertigo (BPPV).
Demet Aygun, Seyma Dumur, Mehmet Nuri Elgormus, Mehmet Serkan Alpaslan, Hafize Uzun   +4 more
doaj   +1 more source