Results 201 to 210 of about 77,458 (359)
Engineering Liposomes for Neurodegenerative Diseases: Targeted Delivery and Regenerative Potential
ChemNanoMat, EarlyView.Liposomal nanocarriers offer therapeutic promise for neurodegenerative diseases by encapsulating diverse agents such as neurotrophic factors and mRNA while targeting the blood‐brain barrier. Designed to stimulate neuronal repair and restore function, these lipid vesicles advance strategies for optimized design and central nervous system delivery ...
Oybek Ashirov +3 more
wiley +1 more source
Vitamin D supplementation improved physical growth and neurologic development of Preterm Infants receiving Nesting Care in the neonatal Intensive Care Unit [PDF]
, 2023 Weiqin Tang +5 more
openalex +1 more source
Annals of the Child Neurology Society, EarlyView.ABSTRACT Background Pathogenic CYFIP2 variants cause developmental and epileptic encephalopathy (DEE), characterized by early‐onset intractable epilepsy and developmental delay. The disease course has not been delineated. Codon Arg87 is a de novo mutational hotspot associated with a severe DEE phenotype via gain‐of‐function mechanisms. Currently, there
Michaela Squire +3 more
wiley +1 more source
Impact of Vitamin D and IL-1β on Quality of Life in Pediatric Drug-Resistant Epilepsy
Journal of Multidisciplinary HealthcareJohannes Harlan Saing,1 Dina Keumala Sari,2 Supriatmo,1 Aida Fitri,3 Muhammad Arief Pratama4 1Department of Pediatrics, Faculty of Medicine, Universitas Sumatera Utara, Medan, North Sumatra, Indonesia; 2Department of Nutrition, Faculty of Medicine ...
Saing JH +4 more
doaj
Clinical Pharmacology in Drug Development, EarlyView.Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee +5 more
wiley +1 more source
International Journal of Eating Disorders, EarlyView.ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder with structural brain alterations; however, the roles of cortical surface area (CSA) and cortical thickness (CTh) during adolescence remain unclear. Building on frequent reports of gray matter reductions in the cingulate cortex and precuneus, this study assesses CSA, CTh, and ...
Irina Jarvers +11 more
wiley +1 more source
A phenomap of TTR amyloidosis to aid diagnostic screening
ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos +4 more
wiley +1 more source
Nature and Science of SleepYi-An Chen,1,2 Wen-Jui Chang,1,3 Ting-Wei Liao,4 Wei-Syun Hung,1 Pi-Hung Tung,1,5 Shih-Wei Lin,1 Han-Chung Hu,1,6 Ning-Hung Chen,1,6 Ji-Tseng Fang,7 Li-Pang Chuang1,2,6 On behalf of the Integrated Systematic Geriatric Medicine Information and Solutions ...
Chen YA +9 more
doaj
Deep phenotyping of heart failure with preserved ejection fraction through multi‐omics integration
European Journal of Heart Failure, EarlyView.Deep phenotyping of of heart failure with preserved ejection fraction (HFpEF) through multi‐omics integration. AI, artificial intelligence. Aims Heart failure with preserved ejection fraction (HFpEF) has become the predominant form of heart failure and a leading cause of global cardiovascular morbidity and mortality.
Jakob Versnjak +15 more
wiley +1 more source