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Vitamin D alleviates neuronal injury in cerebral ischemia-reperfusion via enhancing the Nrf2/HO-1 antioxidant pathway to counteract NLRP3-mediated pyroptosis.

Journal of Neuropathology and Experimental Neurology, 2023
Vitamin D supplementation is reported to have anti-inflammatory and neuroprotective effects during cerebral ischemia-reperfusion injury (CIRI), but the protective mechanism has not been fully elucidated.
Jinling Qiao   +3 more
semanticscholar   +1 more source

Vitamin D Insufficiency is Associated with Higher Incidence of Dementia, a Large Community-Based Retrospective Cohort Study

Journal of Geriatric Psychiatry and Neurology, 2023
Introduction Active metabolite of vitamin D has neuro-immunomodulatory and neuroprotective properties. However, there is still a debate about the potential association between low serum levels of hydroxy-vitamin D and increased risk for dementia ...
David Kiderman   +7 more
semanticscholar   +1 more source

Evidence for the Importance of Vitamin D Status in Neurologic Conditions

Current Treatment Options in Neurology, 2015
Vitamin D status has been proposed as relevant to many neurological disorders. Data suggest that vitamin D may be important for the development of the nervous system, and it also plays a role in neuroimmunology and neuroprotection. Lower levels of circulating 25-hydroxyvitamin D have been linked with increased risk of multiple sclerosis (MS) and ...
Deanna Saylor   +3 more
openaire   +2 more sources

Association between Vitamin D deficiency and Neurologic Outcomes in Patients after Cardiopulmonary Resuscitation

Shock, 2022
ABSTRACT Aim: We investigated the association between vitamin D deficiency and neurologic outcomes after cardiopulmonary resuscitation. Method: Data from the prospective cardiac arrest registry in the emergency department between October 2019 and April 2021 were ...
Bora, Chae   +6 more
openaire   +2 more sources

Vitamin D Deficiency in the Acute Phase of Stroke May Predict Post-stroke Depression: A Systematic Review and Meta-Analysis

Journal of Geriatric Psychiatry and Neurology
Objective To conduct the association between vitamin D levels in the acute phase of stroke and post-stroke depression (PSD) in stroke patients. Methods Five international databases (PubMed, Web of Science, Embase, Ovid MEDLINE(R), Cochrane Library) and ...
Yongjun Tan   +6 more
semanticscholar   +1 more source

The Influence of Vitamin D on Neurodegeneration and Neurological Disorders: A Rationale for its Physio-pathological Actions

Current Pharmaceutical Design, 2020
Vitamin D is a steroid hormone implicated in the regulation of neuronal integrity and many brain functions. Its influence, as a nutrient and a hormone, on the physiopathology of the most common neurodegenerative diseases is continuously emphasized by new studies. This review addresses what is currently known about the action of vitamin D on the nervous
Maria Morello   +7 more
openaire   +6 more sources

Vitamin D deficiency and its role in neurological conditions: A review

Revue Neurologique, 2016
This review exposes recent advances on the role of vitamin D, cholecalciferol, a secosteroid, in the central nervous system. In humans, vitamin D arises from cutaneous transformation of 7-dehydrocholesterol under the effect of UVB exposure or from food intake.
G. Mpandzou   +4 more
openaire   +3 more sources

Indications for the Use of Vitamin D in Everyday Life Clinical Practice in Individuals with Cerebral Palsy

Journal of Neurology Research Reviews & Reports
There is currently an increasing demand for chronic inflammation to be recognized as a comorbidity in cerebral palsy (CP). A broad immunomodulatory and anti- inflammatory strategy in therapy management should be introduced into daily care.
Hans-Klaus Goischke
semanticscholar   +1 more source

Optimizing The Rehabilitation of Patients With Guillain-Barré Syndrome After Diagnosis Through Early Vitamin D Supplementation

Neurology and Neuroscience
Although Guillain-Barré syndrome (GBS) has been known and intensively described for over 100 years, the therapist cannot predict the course of the acute disease, a subsequent autoimmune remission phase or a degenerative late phase after diagnosis.
Hans-Klaus Goischke
semanticscholar   +1 more source

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