Results 131 to 140 of about 95,643 (257)

Exploring the potential of ucuúba (Virola surinamensis) seed fat

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Ucuúba (Virola surinamensis) fat is an important income source for Amazonian communities. Local businesses typically process whole seeds for fat extraction; however, seed structural integrity may influence extraction efficiency and fat quality.
Juan David Marmolejo Tascón, Eduardo Macedo de Melo, Jane Mara Block, Cristiano José de Andrade, Sandra Regina Salvador Ferreira   +4 more
wiley   +1 more source

Long‐term impact of Elexacaftor/Tezacaftor/ivacaftor on pulmonary, nutritional and metabolic outcomes in homozygous F508del cystic fibrosis patients: A real‐world cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta, Luigi Angelo Fiorito, Roberta Vescovo, Anna Virgilio, Giulia Amato, Giuseppe Cimino   +5 more
wiley   +1 more source

Analysis of interstitial lung disease in pharmacovigilance databases: Coding challenges and interpretation biases—An update

British Journal of Clinical Pharmacology, EarlyView.
Aim Clinically, interstitial lung disease (ILD) is a heterogeneous group of respiratory disorders. Due to their low incidence, pharmacovigilance database analysis is useful to detect them. Precise diagnosis is challenging as well as coding in these databases. Query criteria are among the key elements for a good signal detection.
Romane Freppel, Adeline Benis, Philippe Bonniaud, Jean‐Luc Faillie, Aurélie Grandvuillemin   +4 more
wiley   +1 more source

Vitamin D and people with intellectual disability [PDF]

, 2008
Copyright © 2008 Royal Australian College of General Practitioners Copyright to Australian Family Physician. Reproduced with permission. Permission to reproduce must be sought from the publisher, The Royal Australian College of General Practitioners ...
Downs, J., Durvasula, S., Leonard, H., Nugent, M., Vanlint, S.   +4 more
core  

The quantitative impact of metabolism‐inhibiting drugs on the occurrence of adverse drug reactions—A backward selection approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The quantitative effect of several inhibitory drugs on the development of adverse drug reactions (ADRs) is currently difficult to estimate. Our aim was to identify metabolic pathways, which, when inhibited, increase the risk for certain ADRs, and to use this system to consider comedication at individual level. Methods Data of a prospective
Judith Berres, Justyna Wozniak, Hannah Fölsch, Anja Knueppel‐Ruppert, Verena Graeff, Andrea Kriegisch‐Stumpf, Harald Dormann, Julia C. Stingl, Katja S. Just   +8 more
wiley   +1 more source

LABRAD : Vol 35, Issue 2 - June 2010 [PDF]

, 2010
The Atypical Lymphocytes High Performance Liquid Chromatography (HPLC): An Effective Tool for the Diagnosis of Various Hemoglobinopathies Platelet Transfusions: What We Need to Know Measuring Homocysteine Levels Parathyroid Hormone: A Marker of Vitamin D
Aga Khan University Hospital, Karachi
core   +1 more source

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

Association of severity of primary open-angle glaucoma with serum vitamin D levels in patients of African descent. [PDF]

, 2019
PurposeTo study the relationship between primary open-angle glaucoma (POAG) in a cohort of patients of African descent (AD) and serum vitamin D levels.MethodsA subset of the AD and glaucoma evaluation study III (ADAGES III) cohort, consisting of 357 ...
ADAGES III Genomics Study Group, Arzumanyan, Zorayr, Ayyagari, Radha, Chen, Yii-der I, Dirkes, Keri, Dubiner, Harvey, Feldman, Robert, Girkin, Christopher A, Guo, Xiuqing, Hai, Yang, Hammel, Naama, Holman, Matt, Liebmann, Jeffrey M, Rotter, Jerome I, Slight, Rigby, Taylor, Kent D, Weinreb, Robert N, Zangwill, Linda M   +17 more
core  

Advancing Malic Acid Production of Aspergillus oryzae: Combined Process Optimization and Application of Various Substrates

Biotechnology and Bioengineering, EarlyView.
ABSTRACT In light of climate change and growing resource scarcity, microbial production of organic acids offers a sustainable alternative to fossil‐based chemical synthesis. In this study, malic acid production by Aspergillus oryzae was optimized through cultivation temperature adjustment and biotin supplementation, while organic acid formation from ...
Lukas Hartmann, Anke Neumann, Dirk Holtmann, Björn Vater, Thomas Hahn, Susanne Zibek, Katrin Ochsenreither   +6 more
wiley   +1 more source

An analytical longitudinal observational study on the association of Vitamin D insufficiency in subjects with primary (idiopathic) demyelinating optic neuritis using visual evoked potential and optical coherence tomography

Asian Journal of Medical Sciences
Background: Optic neuritis (ON) is an acute and often immune-mediated inflammatory condition of the optic nerve. Vitamin D acts as an anti-inflammatory agent and may confer neuroprotection.
Nirja Agasti , Amar Kumar Misra , Manamita Mandal , Bijendra Mohanty , Soumit Roy , Joydeep Mukherjee , Jasodhara Chaudhuri   +6 more
doaj   +1 more source