Results 81 to 90 of about 95,643 (257)

Profiling Localized Immunomodulation and Drug Biodistribution within a Subcutaneous Vascularized Niche for Cell Transplantation

Advanced Science, EarlyView.
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza, Simone Capuani, Melissa A. Willman, Alexander Rabassa, Ashley L. Joubert, Tommaso Bo, Letizia Franco, Marzia Conte, Ana L. Anaya‐García, Gabrielle E. Rome, Rim Ouni, Henry J. Seaborne, Camden A. Caffey, Dora M. Berman, Junjun Zheng, Jesus Paez‐Mayorga, Corrine Ying Xuan Chua, Shu Hsia Chen, Norma S. Kenyon, Alessandro Grattoni   +19 more
wiley   +1 more source

Effect of low energy diet for eight weeks to adults with overweight or obesity on folate, retinol, vitamin B₁₂, D and e status and the degree of inflammation: a post hoc analysis of a randomized intervention trial [PDF]

, 2018
Background Obesity is associated with vitamin insufficiency and low grade inflammation. The purpose of this study was to investigate the effect of weight loss on folate, retinol, vitamin B12, D and E status and the degree of inflammation.
Astrup, Arne, Bügel, Susanne, Geiker, Nina Rica Wium, Jakobsen, Jette, Kjoelbaek, Louise, Larsen, Lesli H., Lorenzen, Janne Kunchel, Raben, Anne, Ritz, Christian, Veller, Mette   +9 more
core   +2 more sources

Self‐Amplifying Redox Cycle Triggers Ferroptosis/Cuproptosis Synergy for Enhanced Bacterial Eradication

Advanced Science, EarlyView.
This study designs a targeted nanocomposite (ct@HMCF‐Dex) that responds to acidic infection microenvironments, releasing components which amplify oxidative stress. It disrupts bacterial redox balance, chelates metals to sustain lipid peroxidation, and synergistically induces cuproptosis/ferroptosis‐like death.
Zehui Xiao, Shaolong Qiu, Jiangli Cao, Jifeng Liu, Zhiyong Song, Ting Du, Xinjun Du   +6 more
wiley   +1 more source

The Relationship of Vitamin D Status with Body Mass Index among Obese Adults

Haseki Tıp Bülteni, 2013
Aim: In this study, we aimed to determine vitamin D levels among obese adults and to investigate its relationship with body mass index (BMI). Methods: We retrospectively reviewed the medical records of obese adult patients who were admitted to Hasköy
Cenk Aypak, Hülya Yıkılkan, Murat Dicle   +2 more
doaj   +1 more source

Pancreatic exocrine insufficiency after bariatric surgery [PDF]

, 2017
Morbid obesity is a lifelong disease, and all patients require complementary follow-up including nutritional surveillance by a multidisciplinary team after bariatric procedures.
Arnelo, Urban, Haas, Stephan L., Löhr, J. -Matthias, Martin, Lena, Rutkowski, Wiktor, Thorell, Anders, Valente, Roberto, Vujasinovic, Miroslav   +7 more
core   +1 more source

Preparation, Component Identification, and Antioxidant Activity of Anthocyanins From Punica granatum “Tunisia”

AgriFood: Journal of Agricultural Products for Food, EarlyView.
The preparation for Tunisian pomegranate anthocyanin extract. The molecular mechanisms underlying the antioxidant effects of these compounds were investigated using network pharmacology and molecular docking. Antioxidant activity was evaluated through DPPH, ABTS, and FRAP assays, whereas the effects on oxidative stress and inflammation were examined in
Jing Zhang, Xu‐han Yang, Meng‐qi Zhang, Xu Guo, Ning‐yang Li, Fang‐yu Long, Chao Liu   +6 more
wiley   +1 more source

Vitamin D Insufficiency in Overweight and Obese Children and Adolescents

Frontiers in Endocrinology, 2019
Excessive body weight and obesity in childhood and adolescence are becoming more and more important unfavorable factors that entail extremely adverse consequences and require close attention of physicians of any specialty.
Irina Zakharova, Leonid Klimov, Victoria Kuryaninova, Irina Nikitina, Svetlana Malyavskaya, Svetlana Dolbnya, Anna Kasyanova, Roza Atanesyan, Marina Stoyan, Anastasiya Todieva, Galina Kostrova, Andrey Lebedev   +11 more
doaj   +1 more source

Association of Vitamin D3 Level with Breast Cancer Risk and Prognosis in African-American and Hispanic Women. [PDF]

, 2017
Background: This study investigated the association of vitamin D3 levels with breast cancer risk and progression in African-Americans and Hispanics. Methods: A total of 237 African-American (Cases = 119, Control = 118) and 423 Hispanic women (Cases = 124,
Chlebowski, Rowan, Clayton, Sheilah, Sarkissyan, Marianna, Vadgama, Jaydutt V, Wu, Yanyuan   +4 more
core   +2 more sources

Fermented Citrus as a Functional Food Matrix: Evaluating Probiotic, Prebiotic, and Postbiotic Potential

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Fermented citrus transforms bioactive compounds into metabolites with probiotic and prebiotic properties, enhancing gut health, immunity, and metabolic balance. This review highlights fermentation's role in developing sustainable, health‐promoting functional foods while addressing challenges in process optimization, sensory quality, and commercial ...
Sony Kumari, Rahel Debbarma, Shakil Haque, Himalay Baruah   +3 more
wiley   +1 more source

Interpretation of A Focus Shift From Sarcopenia to Muscle Health in the Asian Working Group for Sarcopenia 2025 Consensus Update

AGING MEDICINE, EarlyView.
The AWGS 2025 consensus shifts focus from diagnosing sarcopenia to promoting muscle health across the lifespan. It simplifies diagnosis to low muscle mass plus low strength, expands screening to middle‐aged adults, and integrates muscle health into the WHO ICOPE framework for early intervention and healthy aging.
Bi Jianghan, Li Jiaojiao, Kang Lin
wiley   +1 more source