Results 211 to 220 of about 168,717 (262)

Vitamin D/vitamin D receptor, autophagy, and infection.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2022
Vitamin D plays an important role in mineral and bone homeostasis, immune responses, cardiovascular function and keratinocyte proliferation and differentiation. Vitamin D performs most of its functions by binding to vitamin D receptors (VDR), which interact with other intracellular signaling pathways to regulate bone metabolism, inflammation, immunity,
Yu, Hou, Jinghui, Li, Chao, Deng
openaire   +1 more source

Vitamin D and the vitamin D receptor in liver pathophysiology

Clinics and Research in Hepatology and Gastroenterology, 2011
Vitamin D through the vitamin D nuclear receptor (VDR) plays a key role in mineral ion homeostasis. The liver is central in vitamin D synthesis, however the direct involvement of the vitamin D-VDR axis on the liver remains to be evaluated. In this review, we will describe vitamin D metabolism and the mechanisms of homeostatic control.
Zúñiga, Silvia, Firrincieli, Delphine, Housset, Chantal, Chignard, Nicolas   +3 more
openaire   +2 more sources

Vitamin D Receptor–DNA Interactions

2004
The vitamin D receptor (VDR) is a member of the steroid and nuclear hormone receptor superfamily of eukaryotic transcription factors and binds target DNA, or response elements, as a homodimer or heterodimer with the 9-cis retinoid X receptor (RXR).
Paul L, Shaffer, Daniel T, Gewirth
openaire   +2 more sources

Human prostatic urethra expresses vitamin D receptor and responds to vitamin D receptor ligation

Journal of Endocrinological Investigation, 2010
Chronic inflammation is now considered a determinant of benign prostatic hyperplasia (BPH), promoting, together with the hormonal milieu, prostate overgrowth and lower urinary tract symptoms (LUTS). Prostatic urethra actively participates in determining progression of LUTS associated with BPH.To investigate the expression of the vitamin D receptor (VDR)
COMEGLIO, PAOLO, A. K. Chavalmane, FIBBI, BENEDETTA, FILIPPI, SANDRA, M. Marchetta, MARINI, MIRCA, MORELLI, ANNAMARIA, G. Penna, VIGNOZZI, LINDA, VANNELLI, GABRIELLA, L. Adorini, MAGGI, MARIO   +11 more
openaire   +2 more sources

The Function of Vitamin D Receptor in Vitamin D Action

Journal of Biochemistry, 2000
Vitamin D has roles in a variety of biological actions such as calcium homeostasis, cell proliferation and cell differentiation to many target tissues. Most of these biological actions of vitamin D are now considered to be exerted through the nuclear vitamin D receptor (VDR)-mediated control of target genes.
openaire   +2 more sources

Vitamin D receptor polymorphisms and diseases

Clinica Chimica Acta, 2006
The vitamin D endocrine system is central to the control of bone and calcium homeostasis. Thus, alterations in the vitamin D pathway lead to disturbances in mineral metabolism. Furthermore, a role for vitamin D has been suggested in other diseases, like cancer, diabetes and cardiovascular disease.
Jose M, Valdivielso, Elvira, Fernandez
openaire   +2 more sources

Vitamin D and toll like receptors

Life Sciences, 2018
It has been demonstrated that vitamin D (VD) significantly modulates immune responses. Toll like receptors (TLRs) are the main innate immunity receptors which are expressed on the cell membrane and intracellular vesicles and recognize several pathogen associated molecular patterns (PAMPs) and damage associated molecular patterns (DAMPs) to induce ...
Mohammad Kazemi Arababadi, Reza Nosratabadi, Gholamreza Asadikaram   +2 more
openaire   +2 more sources

Vitamin D Receptors And Parathyroid Glands

Endocrine Practice, 2011
To describe the function and metabolism of the vitamin D hormone and the role of the vitamin D receptor and the calcium-sensing receptor in the secretion of parathyroid hormone.A review of the literature was undertaken regarding the function and metabolism of vitamin D; the role of the vitamin D receptor and calcium-sensing receptor in the secretion of
Christine S, Landry, Mary D, Ruppe, Elizabeth G, Grubbs   +2 more
openaire   +2 more sources

Vitamin D Receptor Activation: Clinical Outcomes

2011
Vitamin D has been recognized for years as a key player in the control of bone metabolism through the regulation of calcium and phosphate homeostasis. Vitamin D deficiency appears to be common in the general population as a result of decreased dietary intake, diminished absorption, or limited exposure to sunlight.
Adrian, Covic, Mugurel, Apetrii
openaire   +2 more sources

Vitamin D Receptor Polymorphisms and Cancer

2020
Increasing scientific evidence supports the link between vitamin D and cancer risk. The active metabolite 1,25(OH)2D exerts its activity by binding to the vitamin D receptor (VDR), an intracellular receptor that mediates transcriptional activation and repression of target genes. The binding of 1,25(OH)2D to VDR is able to regulate hundreds of different
Patrizia, Gnagnarella, Sara, Raimondi, Valentina, Aristarco, Harriet Ann, Johansson, Federica, Bellerba, Federica, Corso, Sara, Gandini   +6 more
openaire   +2 more sources