Results 41 to 50 of about 275,782 (257)

Reduction of parathyroid hormone with vitamin D supplementation in blacks: A randomized controlled trial [PDF]

, 2015
BACKGROUND: Response of parathyroid hormone (PTH) to vitamin D supplementation is determined by the baseline PTH level and change in vitamin D status. Conflicting reports in Blacks exist on the PTH response to vitamin D to supplementation.
Agboola, Foluso, Bennett, Gary G, Chan, Andrew T, Chandler, Paulette D, Drake, Bettina F, Emmons, Karen M, Fuchs, Charles S, Giovannucci, Edward L, Hollis, Bruce W, Ng, Kimmie, Scott, Jamil B   +10 more
core   +2 more sources

25(OH)D3-enriched or fortified foods are more efficient at tackling inadequate vitamin D status than vitamin D3 [PDF]

, 2017
The ability to synthesise sufficient vitamin D through sunlight in human subjects can be limited. Thus, diet has become an important contributor to vitamin D intake and status; however, there are only a few foods (e.g.
Bates, Cavalli, D. Ian Givens, Dueland, Jing Guo, Jones, Julie A. Lovegrove, McCance, Nair, Torregrosa   +9 more
core   +2 more sources

Vitamin D Status and its Association with Morbidity including Wasting and Opportunistic Illnesses in HIV-Infected Women in Tanzania. [PDF]

, 2011
Vitamin D has a potential role in preventing HIV-related complications, based on its extensive involvement in immune and metabolic function, including preventing osteoporosis and premature cardiovascular disease.
Adeyemi OM, Chlebowski RT, Cox D, Diggle P, Donna Spiegelman, Eduardo Villamor, Edward L. Giovannucci, Ellen Hertzmark, Ferdinand M. Mugusi, Finkelstein JL, Gernard I. Msamanga, Guenter P, Hsu JW, James WP, Julia L. Finkelstein, Miettinen O, Saurabh Mehta, Stroder J, Wafaie W. Fawzi, WHO   +19 more
core   +2 more sources

Vitamin D Receptor Gene Polymorphisms Modify Cardiometabolic Response to Vitamin D Supplementation in T2DM Patients [PDF]

, 2017
There is conflicting evidence on the favorable effects of vitamin D supplementation on metabolic profile in Type 2 diabetes mellitus (T2DM) patients and this might be due to genetic variations in vitamin D receptors (VDRs). Thus, we studied the metabolic
A Sadiya, AG Pittas, AG Uitterlinden, B-W Ogunkolade, D Bikle, D Zehnder, EM Colin, ES Ford, FJ Gonzalez, GC Major, H Mazahery, H Wang, J Mitri, J Smolders, JA Johnson, JC Seida, MF Holick, ML McCullough, MP Ponda, NG Forouhi, NM Al-Daghri, P George, P Karhapää, P Knekt, P Munoz-Aguirre, PK Manchanda, PR Hurst von, PW Jurutka, R Bland, R Scragg, S Palomba, S-M Orton, TR Neyestani, U Zeitz, X Sun   +34 more
core   +1 more source

No effects of oral vitamin D supplementation on non-alcoholic fatty liver disease in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled trial [PDF]

, 2016
Background: Non-alcoholic fatty liver disease (NAFLD) is the most common hepatic disorder worldwide, reaching prevalence up to 90 % in obese patients with type 2 diabetes (T2D), and representing an independent risk factor for cardiovascular mortality ...
ANGELICO, Francesco, BARCHETTA, ILARIA, BARONI, Marco Giorgio, BERTOCCINI, LAURA, CATALANO, Carlo, CAVALLO, Maria Gisella, CIMINI, FLAVIA AGATA, DEL BEN, Maria, DI MARTINO, MICHELE, FRAIOLI, Antonio, LA TORRE, Giuseppe, Morini, Sergio, PANIMOLLE, FRANCESCA, PERRI, LUDOVICA, SAULLE, ROSELLA, TIBERTI, Claudio   +15 more
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Association between vitamin D level and pediatric inflammatory bowel disease: A systematic review and meta-analysis

Frontiers in Pediatrics, 2023
BackgroundPrevious studies have reported that the incidence of pediatric inflammatory bowel disease (IBD) is related to vitamin D, but it is still unclear.
Yan-hong Sun, Dan-dan Tian, Jian-ming Zhou, Qing Ye   +3 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Prospective cohort study of vitamin D deficiency in pregnancy: Prevalence and limited effectiveness of 1000 IU vitamin D supplementation

Women's Health
Background: Vitamin D deficiency is highly prevalent worldwide among pregnant women. Although vitamin D supplementation is effective in improving vitamin D status, the safety and optimal dosing of vitamin D supplementation during pregnancy remain less ...
Rasha Mohammed Abdelmageed, Suha Majeed Mohammed Hussein, Shamil Mohamed Anamangadan, Rola Walid Mahmoud Abdullah, Lubna Rauf, AlAnoud Saleh AlFehaidi, Ehab Hamed   +6 more
doaj   +1 more source

Vitamin D: Newer Concepts of Its Metabolism and Function at the Basic and Clinical Level. [PDF]

, 2020
The interest in vitamin D continues unabated with thousands of publications contributing to a vast and growing literature each year. It is widely recognized that the vitamin D receptor (VDR) and the enzymes that metabolize vitamin D are found in many ...
Bikle, Daniel D
core   +1 more source