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Vitamin K Deficiency and Breast-feeding

Archives of Pediatrics & Adolescent Medicine, 1983
Hemorrhagic disease of the newborn was described in 1894 by Townsend.1It occurs in the first week of life, independent of trauma, anoxia, or infection, and appears to be a self-limiting condition if unassociated with life-threatening hemorrhage. It is caused by vitamin K deficiency, which has been reported in several infants 4 to 8 weeks old.
M E, O'Connor   +3 more
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Vitamin K Deficiency in Infancy in Japan

Pediatrics, 1984
To the Editor.— Lane et al1 reported a case of fatal intracranial hemorrhage in a normal infant who was retrospectively determined to have had vitamin K deficiency. This paper rings the alarm against the tendency toward cessation of routine prophylactic administration of vitamin K at birth for full-term infants.
T, Nagao, K, Nakayama
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Prevention of Vitamin K Deficiency Bleeding

Journal of Midwifery & Women's Health, 2016
The risk that a newborn will develop vitamin K deficiency bleeding is 1700/100,000 (one out of 59) if vitamin K is not administered. When intramuscular vitamin K is administered, the risk of vitamin K deficiency bleeding is reduced to 1/100,000. While women may have misconceptions about vitamin K prophylaxis for their newborns, health care providers ...
Julia C, Phillippi   +3 more
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Vitamin K Deficiency in Breastfed Infants

The Journal of Pediatrics, 1985
Vitamin K is required for gamma carboxylation of a number of proteins, most of which are involved in haemostasis. Bleeding is the main clinical problem observed in vitamin K deficiency.
R, von Kries   +3 more
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Vitamin K deficiency from dietary vitamin K restriction in humans

The American Journal of Clinical Nutrition, 1988
Vitamin K is required for the maintenance of normal hemostatic function. Ten college-aged male subjects chose diets restricted in vitamin K content for 40 d. Median phylloquinone intakes based on analysis of food composites dropped from 82 micrograms/d during the prestudy period to 40 and 32 micrograms/d at d 9 and 27 of dietary restriction ...
J W, Suttie   +4 more
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Oral anticoagulation and vitamin K deficiency

Hämostaseologie, 2014
SummaryA 61-year old woman with atrial fibrillation developed macrohaematuria during anticoagulant treatment with a direct oral factor Xa inhibitor for stroke prevention. Abnormal results of coagulation assays were first interpreted as an effect of the anticoagulant. However, upon further testing diagnosis of vitamin K deficiency was established. After
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Prevention of vitamin K deficiency in infancy by weekly administration of vitamin K

Acta Paediatrica, 1993
Vitamin K prophylaxis has been developed to prevent classic haemorrhagic disease of the newborn. Single vitamin K administration after birth has been reported to fail, resulting in late haemorrhagic disease of the newborn. The preventive effect of oral administration of vitamin K1 1 mg, repeated weekly during the first three months of life, was studied
E A, Cornelissen   +4 more
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Vitamin K Absorption Capacity and Its Association With Vitamin K Deficiency

Archives of Pediatrics & Adolescent Medicine, 1989
We measured plasma vitamin K concentrations in 194 5-day-old infants three hours after administration of a 4-mg dose of vitamin K (menaquinone-4, Kaytwo syrup, Eisai Co Ltd, Tokyo, Japan). We investigated association with other factors contributing to vitamin K deficiency.
T, Shinzawa   +3 more
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Vitamin K Deficiency and Hemorrhage in Infancy

Clinics in Perinatology, 1995
Hemorrhage in the infant from vitamin K deficiency is still a concern in pediatrics. Vitamin K given intramuscularly will largely prevent hemorrhagic disease in the newborn, even in infants who are exclusively breast-fed and are thus at the greatest risk for bleeding.
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