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Vitamin K Deficiency and Breast-feeding
Archives of Pediatrics & Adolescent Medicine, 1983Hemorrhagic disease of the newborn was described in 1894 by Townsend.1It occurs in the first week of life, independent of trauma, anoxia, or infection, and appears to be a self-limiting condition if unassociated with life-threatening hemorrhage. It is caused by vitamin K deficiency, which has been reported in several infants 4 to 8 weeks old.
M E, O'Connor +3 more
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Vitamin K Deficiency in Infancy in Japan
Pediatrics, 1984To the Editor.— Lane et al1 reported a case of fatal intracranial hemorrhage in a normal infant who was retrospectively determined to have had vitamin K deficiency. This paper rings the alarm against the tendency toward cessation of routine prophylactic administration of vitamin K at birth for full-term infants.
T, Nagao, K, Nakayama
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Prevention of Vitamin K Deficiency Bleeding
Journal of Midwifery & Women's Health, 2016The risk that a newborn will develop vitamin K deficiency bleeding is 1700/100,000 (one out of 59) if vitamin K is not administered. When intramuscular vitamin K is administered, the risk of vitamin K deficiency bleeding is reduced to 1/100,000. While women may have misconceptions about vitamin K prophylaxis for their newborns, health care providers ...
Julia C, Phillippi +3 more
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Vitamin K Deficiency in Breastfed Infants
The Journal of Pediatrics, 1985Vitamin K is required for gamma carboxylation of a number of proteins, most of which are involved in haemostasis. Bleeding is the main clinical problem observed in vitamin K deficiency.
R, von Kries +3 more
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Vitamin K deficiency from dietary vitamin K restriction in humans
The American Journal of Clinical Nutrition, 1988Vitamin K is required for the maintenance of normal hemostatic function. Ten college-aged male subjects chose diets restricted in vitamin K content for 40 d. Median phylloquinone intakes based on analysis of food composites dropped from 82 micrograms/d during the prestudy period to 40 and 32 micrograms/d at d 9 and 27 of dietary restriction ...
J W, Suttie +4 more
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Oral anticoagulation and vitamin K deficiency
Hämostaseologie, 2014SummaryA 61-year old woman with atrial fibrillation developed macrohaematuria during anticoagulant treatment with a direct oral factor Xa inhibitor for stroke prevention. Abnormal results of coagulation assays were first interpreted as an effect of the anticoagulant. However, upon further testing diagnosis of vitamin K deficiency was established. After
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Prevention of vitamin K deficiency in infancy by weekly administration of vitamin K
Acta Paediatrica, 1993Vitamin K prophylaxis has been developed to prevent classic haemorrhagic disease of the newborn. Single vitamin K administration after birth has been reported to fail, resulting in late haemorrhagic disease of the newborn. The preventive effect of oral administration of vitamin K1 1 mg, repeated weekly during the first three months of life, was studied
E A, Cornelissen +4 more
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VITAMIN-K DEFICIENCY IN THE NEWBORN
The Lancet, 1977van Doorm, J.M., Hemker, H.C.
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Vitamin K Absorption Capacity and Its Association With Vitamin K Deficiency
Archives of Pediatrics & Adolescent Medicine, 1989We measured plasma vitamin K concentrations in 194 5-day-old infants three hours after administration of a 4-mg dose of vitamin K (menaquinone-4, Kaytwo syrup, Eisai Co Ltd, Tokyo, Japan). We investigated association with other factors contributing to vitamin K deficiency.
T, Shinzawa +3 more
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Vitamin K Deficiency and Hemorrhage in Infancy
Clinics in Perinatology, 1995Hemorrhage in the infant from vitamin K deficiency is still a concern in pediatrics. Vitamin K given intramuscularly will largely prevent hemorrhagic disease in the newborn, even in infants who are exclusively breast-fed and are thus at the greatest risk for bleeding.
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