Vitamin K Deficiency Bleeding in Infancy. [PDF]
Nutrients, 2020 Vitamin K is essential for the synthesis of few coagulation factors. Infants can easily develop vitamin K deficiency owing to poor placental transfer, low vitamin K content in breast milk, and poor intestinal absorption due to immature gut flora and malabsorption.
Araki S, Shirahata A.
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Midwives' Perspectives about Vitamin K Prophylaxis Against Vitamin K Deficiency Bleeding of the Newborn. [PDF]
Matern Child Health J, 2022 The American Academy of Pediatrics recommends one intramuscular (IM) vitamin K injection at birth to prevent Vitamin K Deficiency Bleeding of the Newborn (VKDB). Among factors associated with IM vitamin K refusal, investigators have reported an increased frequency of IM vitamin K refusal among parents who select midwife-assisted deliveries.
Loyal J, Danziger P, Wood KE.
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Early Vitamin K Deficiency Bleeding in a Neonate Associated with Maternal Acute Fatty Liver of Pregnancy [PDF]
American Journal of Perinatology Reports, 2015 Introduction Acute fatty liver of pregnancy (AFLP) is a rare but potentially fatal condition occurring in the third trimester or early postpartum period. It is characterized by microvesicular fatty infiltration of the liver.
Shreyas Arya +3 more
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Vitamin K deficiency bleeding of newborn masquerading haemophilia B. [PDF]
Sudan J Paediatr, 2020 The term infant is remarkably resistant to bleeding despite physiologically low levels of procoagulant proteins. However, because of their unique haemostatic systems, neonates are vulnerable to haemorrhagic disorders. The prevention of early vitamin K deficiency bleeding (VKDB) of newborn by oral or parenteral administration of vitamin K has been well ...
Kumar M, Kumar S, Bajpayi S, Kumari R.
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Hereditary combined deficiency of vitamin K–dependent clotting factors presenting as postoperative haemorrhage in a Syrian adolescent: a likely VKCFD type 2 phenotype [PDF]
European Journal of Case Reports in Internal MedicineHereditary combined deficiency of vitamin K–dependent clotting factors (VKCFD) is a rare autosomal recessive disorder characterized by reduced activity of factors II, VII, IX, and X despite normal vitamin K levels.
Mahmoud Alhamadeh Alswij +5 more
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Superwarfarin Rodenticide Poisoning due to Consumption of Exotic Animals: A Case Report [PDF]
Case Reports in HematologyPoisoning from superwarfarin rodenticides should be considered in patients with unexplained bleeding due to vitamin K deficiency, with no other history of coagulopathy or anticoagulant use.
Batoul Sadek +6 more
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Vitamin K prophylaxis for prevention of vitamin K deficiency bleeding: a systematic review. [PDF]
J Perinatol, 2016 We conducted a systematic review to evaluate the burden of late vitamin K deficiency bleeding (VKDB) and the effect of vitamin K prophylaxis on the incidence of VKDB. We searched MEDLINE and other electronic databases, and included all observational studies including population surveys as well as randomized controlled trials (RCT).
Sankar MJ +5 more
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Vitamin K deficiency bleeding in an apparently healthy newborn infant: the compelling need for evidence-based recommendation [PDF]
Italian Journal of Pediatrics, 2019 Background Vitamin K is a key point for guarantee normal blood clotting and its level in newborns is commonly low, so a supplementation after delivery is mandatory.
Simone Ceratto, Francesco Savino
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Old scars, new bleeds: revisiting coagulopathy in quiescent Crohn’s disease [PDF]
European Journal of Case Reports in Internal MedicineBackground: Vitamin K serves as a critical coenzyme in the gamma-carboxylation of clotting factors II, VII, IX, and X, underscoring its essential role in the coagulation cascade.
Simran Patel +4 more
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Prophylactic vitamin K for the prevention of vitamin K deficiency bleeding in preterm neonates. [PDF]
Cochrane Database Syst Rev, 2018 Vitamin K is necessary for the synthesis of coagulation factors. Term infants, especially those who are exclusively breast fed, are deficient in vitamin K and consequently may have vitamin K deficiency bleeding (VKDB). Preterm infants are potentially at greater risk for VKDB because of delayed feeding and subsequent delay in the colonization of their ...
Ardell S, Offringa M, Ovelman C, Soll R.
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