Results 91 to 100 of about 61,417 (351)
Advanced Science, EarlyView.PtRhIr/Ru SAN@M nanozymes cross the blood–brain barrier and selectively accumulate in hemorrhagic brain regions. By mimicking multiple enzyme activities, they attenuate oxidative stress, modulate microglial polarization toward an anti‐inflammatory phenotype, inhibit ferroptosis, and promote neuronal repair.
Jiebo Li +17 more
wiley +1 more source
DUA KASUS ACQUIRED PROTHROMBIN COMPLEX DEFICIENCY DENGAN PERDARAHAN INTRAKRANIAL : LAPORAN KASUS
JKS (Jurnal Kedokteran Syiah Kuala), 2017 Abstrak. Acquired Prothrombin Complex Deficiency (APCD) merupakan perdarahan spontan yang disebabkan oleh penurunan aktivitas faktor koagulasi yang tergantung vitamin K (faktor II, VII, IX dan X), sedangkan aktivitas faktor koagulasi lain, kadar ...
Jufitriani Ismy
doaj +1 more source
Atherothrombosis and Oxidative Stress: Mechanisms and Management in Elderly [PDF]
, 2017 Significance: The incidence of cardiovascular events (CVEs) increases with age, representing the main cause of death in an elderly population. Aging is associated with overproduction of reactive oxygen species (ROS), which may affect clotting and ...
Carnevale, Roberto +4 more
core +1 more source
Advanced Science, EarlyView.This review outlines association between vasculitis and malignancies and provides practical value for clinicians in distinguishing primary vasculitis from malignancy‐associated forms and optimizing patient surveillance, improving recognition of tumor‐associated vasculitis to reduce the risk of misdiagnosis, supporting more accurate clinical decision ...
Xiaofei Shi +8 more
wiley +1 more source
A case report of congenital factor X deficiency in an adult patient
SAGE Open Medical Case Reports, 2022 Factor X deficiency is one of the rarest coagulation disorders representing 10% of all rare bleeding diseases with a frequency of 1:1,000,000. A 39-year-old male patient with no previous medical conditions was admitted to the hospital with a left carpal ...
Rehab Y AL-Ansari +3 more
doaj +1 more source
European Journal of Pediatrics, 2007 Vitamin K prophylaxis is recommended to prevent the hazard of haemorrhage caused by vitamin K deficiency in newborns. The present Dutch guideline recommends 1 mg of vitamin K1 orally at birth, followed by a daily dose of 25 μg of vitamin K1 from 1 to 13 ...
M. Ijland, R. R. Pereira, E. Cornelissen
semanticscholar +1 more source
Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases
Advanced Science, EarlyView.Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh +17 more
wiley +1 more source
Factor VII deficiency: a rare genetic bleeding disorder in a 7-year-old child: a case report
Journal of Medical Case Reports, 2023 Background Factor VII deficiency is a rare inherited bleeding disorder that has similar clinical presentation to hemophilia. Case report A 7-year-old male child of African origin experienced recurrent nasal bleeding since 3 years of age and recurrent ...
Hajaj Mohamed Salum +8 more
doaj +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Biallelic pathogenic variants in AKR1D1 cause Δ4‐3‐oxosteroid 5β‐reductase deficiency, disrupt bile acid synthesis, and result in Congenital Bile Acid Synthesis defect type 2 (CBAS2). CBAS2 presents in infancy with cholestasis, coagulopathy, and failure to thrive.
Jade Hudson +3 more
wiley +1 more source