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Vitamin K Deficiency Bleeding: An Ounce of Prevention

Neonatal Network, 2020
Vitamin K is a fat-soluble vitamin essential for the formation of factors in the clotting cascade. Newborns are born with insufficient levels of vitamin K, resulting in high risk for vitamin K deficiency bleeding (VKDB). Vitamin K deficiency bleeding can occur in the first week of life (“classic” VKDB) and also between 2 weeks and 3 months of age ...
C. McPherson
openaire   +3 more sources

Vitamin K prophylaxis and vitamin K deficiency bleeding (VKDB) in early infancy

Acta Paediatrica, 1992
The efficacy of vitamin K prophylaxis (1 mg im or sc, or 1–2 mg orally both given as a single dose at birth) in the prevention of vitamin K deficiency bleeding in early infancy was estimated in Germany during a 15‐month period between 1988 and 1989. Cases were identified by a survey of all paediatric hospitals and population denominators by a survey of
R, von Kries, U, Göbel
openaire   +3 more sources

Late form of Vitamin K Deficiency Bleeding in Germany

Klinische Pädiatrie, 1995
The evaluation of the disease of vitamin K deficiency bleeding (VKDB).108 reported cases between 1980 and 1990 from Germany.VKDB occurs preferentially (90%) in fully breastfed infants, males are affected nearly twice as often as females. The peak age is four weeks; the majority (79%) of the infants are between three and seven weeks old.
Sutor, Anton H.   +2 more
openaire   +4 more sources

VITAMIN K DEFICIENCY BLEEDING

Journal of Neonatology, 2003
This letter deals with the problem of vitamin k deficiency bleeding, affecting exclusively breast-fed infants, and with the possible prophylactic choices.
FANARO, Silvia, VIGI, Vittorio
openaire   +3 more sources

Vitamin K Deficiency Bleeding

Advances in Neonatal Care, 2013
Vitamin K deficiency bleeding (VKDB), formerly known as hemorrhagic disease of the newborn (HDN), is a bleeding disorder in neonates that is caused by inadequate serum levels of vitamin K. Vitamin K is a nutrient essential for adequate function of the coagulation cascade.
Christopher W, Woods   +2 more
openaire   +2 more sources

The challenge to define the optimal prophylactic regimen for vitamin K deficiency bleeding in infants.

Acta paediatrica, 2020
Infants are at risk of vitamin K deficiency that may lead to Vitamin K Deficiency Bleeding (VKDB). Although many vitamin K prophylactic regimens have been developed throughout the years, still cases of late form VKBD may occur.
L. Chiara   +2 more
semanticscholar   +2 more sources

Delayed Complementary Feeding as a Risk Factor for Vitamin K Deficiency Bleeding in a 9-Month-Old Infant.

Journal of pediatric hematology/oncology
Vitamin K deficiency bleeding (VKDB) is a well-known entity in the newborn period, classically presenting during the first week of life. VKDB causing massive bleeding beyond 3 months of age, in an otherwise healthy child, is extremely rare.
Ponni G Jayan   +3 more
semanticscholar   +1 more source

Vitamin K prophylaxis and vitamin K deficiency bleeding in the UK

Archives of Disease in Childhood, 2010
Aim To correlate incidence, morbidity and mortality of vitamin K deficiency bleeding (VKDB) with changing practices in vitamin K (VK) prophylaxis in the UK—most recently the withdrawal of Konakion Neonatal in 2006, leaving Konakion MM as the only licenced preparation for prophylaxis in the UK.
A Busfield, R Samuel, A McNinch, J Tripp
openaire   +1 more source

Bleeding and Vitamin K Deficiency

2016
Vitamin K is a cofactor for human glutamic acid carboxylase enzymes in multiple tissues and organs. The dominant vitamin K activity is gamma-carboxylation of selective glutamic acid residues on coagulation factors X, IX, VII, and II. Humans predominantly rely on green vegetable dietary sources of vitamin K rather than synthesis of vitamin K by ...
openaire   +1 more source

Case report of the late-onset Vitamin K deficiency bleeding in a patient with hemophilia A

PEDIATRIA Journal named after G N SPERANSKY
Late-onset Vitamin K deficiency bleeding is a rare disease that develops as a manifestation of Vitamin K deficiency in children from 8 days to 6 months of age with an incidence of 4.4 to 72 cases per 100,000 newborns in countries where prophylaxis with ...
E. M. Golovina   +6 more
semanticscholar   +1 more source

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