Results 51 to 60 of about 17,514 (247)

Oral mixed micellar vitamin K for prevention of late vitamin K deficiency bleeding [PDF]

open access: yesArchives of Disease in Childhood - Fetal and Neonatal Edition, 2003
Objective: To determine whether the use of mixed micellar vitamin K improves the efficacy of the 3 × 2 mg oral vitamin K prophylaxis schedule. Design: Nationwide active surveillance for vitamin K deficiency bleeding (VKDB) complemented with two surveys on the use of the mixed micellar preparation in ...
R, von Kries, A, Hachmeister, U, Göbel
openaire   +2 more sources

Intravital Multimodal Imaging of Human Cortical Organoid Transplantation in a Mouse Model of Chronic Stroke

open access: yesAdvanced Science, EarlyView.
A multimodal intravital imaging platform enables longitudinal tracking of human cortical organoids transplanted into chronic stroke lesions. By combining surgical microscopy, MRI, bioluminescence imaging, and two‐photon fluorescence microscopy, the platform captures graft placement, viability dynamics, and cellular‐scale morphology in vivo, offering a ...
Jinghui Wang   +12 more
wiley   +1 more source

X-Linked Chronic Granulomatous Disease: Initial Presentation with Intracranial Hemorrhage from Vitamin K Deficiency in Infant

open access: yesCase Reports in Pediatrics, 2018
Vitamin K deficiency bleeding (VKDB) is a life-threatening condition and can be found in children as early as neonatal period with early onset intracranial hemorrhage (ICH).
Boonchai Boonyawat   +4 more
doaj   +1 more source

Acquired Factor VII Deficiency Associated With Chronic Myeloid Leukemia Blast Crisis

open access: yesJournal of Investigative Medicine High Impact Case Reports, 2023
Factor VII (FVII) is an important, vitamin K-dependent clotting factor. Acquired FVII deficiency is a rare entity that is associated with serious bleeding complications.
Emily B. Wolf MD   +9 more
doaj   +1 more source

Identification of a Nonribosomal Peptide Analog With Activity Against Multiple Gram‐Positive Bacteria via a Synthetic Bioinformatic Natural Product Discovery Approach

open access: yesAdvanced Science, EarlyView.
The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen   +9 more
wiley   +1 more source

Superwarfarin Rodenticide Poisoning due to Consumption of Exotic Animals: A Case Report

open access: yesCase Reports in Hematology
Poisoning from superwarfarin rodenticides should be considered in patients with unexplained bleeding due to vitamin K deficiency, with no other history of coagulopathy or anticoagulant use.
Batoul Sadek   +6 more
doaj   +1 more source

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

open access: yesAdvanced Science, EarlyView.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang   +8 more
wiley   +1 more source

Vitamin K: the effect on health beyond coagulation – an overview

open access: yesFood & Nutrition Research, 2012
Vitamin K is essential for the synthesis of proteins belonging to the Gla-protein family. To the members of this family belong four blood coagulation factors, which all are exclusively formed in the liver.
Cees Vermeer
doaj   +1 more source

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal   +5 more
wiley   +1 more source

Old scars, new bleeds: revisiting coagulopathy in quiescent Crohn’s disease

open access: yesEuropean Journal of Case Reports in Internal Medicine
Background: Vitamin K serves as a critical coenzyme in the gamma-carboxylation of clotting factors II, VII, IX, and X, underscoring its essential role in the coagulation cascade.
Simran Patel   +4 more
doaj   +1 more source

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