Cellular Proteomes Drive Tissue-Specific Regulation of the Heat Shock Response
G3: Genes, Genomes, Genetics, 2017 The heat shock response (HSR) is a cellular stress response that senses protein misfolding and restores protein folding homeostasis, or proteostasis.
Jian Ma +5 more
doaj +1 more source
Detection of vitellogenin in a subpopulation of sea urchin coelomocytes [PDF]
, 1994 Sea urchin vitellogenin is a high molecular weight glycoprotein, which is the precursor of the major yolk protein present in the unfertilized egg. Vitellogenin processing into the major yolk protein and its further enzymatic cleavage during sea urchin ...
ARIZZA, Vincenzo +4 more
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Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2 [PDF]
, 2014 The antiglycemic drug metformin, widely prescribed as first-line treatment of type II diabetes mellitus, has lifespan-extending properties. Precisely how this is achieved remains unclear.
Billen, Johan +8 more
core +1 more source
Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models
Environmental Toxicology, EarlyView.ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa +9 more
wiley +1 more source
DmCatD, a cathepsin D-like peptidase of the hematophagous insect Dipetalogaster maxima (Hemiptera: Reduviidae): Purification, bioinformatic analyses and the significance of its interaction with lipophorin in the internalization by developing oocytes [PDF]
, 2018 DmCatD, a cathepsin D-like peptidase of the hematophagous insect Dipetalogaster maxima, is synthesized by the fat body and the ovary and functions as yolk protein precursor. Functionally, DmCatD is involved in vitellin proteolysis.
Arrese, Estela L. +8 more
core +1 more source
Developmental environment and age shape macronutrient allocation to eggs and ejaculates
Functional Ecology, EarlyView.Read the free Plain Language Summary for this article on the Journal blog. Abstract Environmental conditions during development can have lasting effects on reproductive investment, but the sex‐ and age‐specific nature of such effects remains poorly understood.
Upama Aich +4 more
wiley +1 more source
Frontiers in Endocrinology, 2020 In this report, we studied the vitellogenin gene family in the whiteleg shrimp Litopenaeus vannamei by transcriptomics, bioinformatics, and molecular biology methods. At least three moderately homologous vitellogenin (Vg) genes (i.e.
Wei Wang +6 more
doaj +1 more source
Insect Science, EarlyView.An intronless version of the white pupae (wp) gene was engineered to restore the wild type brown puparium color in white pupae phenotype mutants of the Mediterranean fruit fly, Ceratitis capitata. Functionality of the minimal gene version (mini‐wp) was verified in vivo, as one copy of mini‐wp successfully restored the wild type phenotype in homozygous ...
Lucas Henrique Figueiredo Prates +4 more
wiley +1 more source
Multicolor transzgenikus zebradánió vonalak létrehozása környezettoxikológiai és farmakológiai tesztekhez = Establishment of multicolor transgenic zebra fish lines for environmental toxicology and pharmacology tests [PDF]
, 2011 A pályázat támogatásával célunk olyan többszörösen transzgenikus zebradánió vonalak létrehozása volt, amelyek a fő toxikológiai célszervekben (máj, érszövet, vér, idegrendszer) fluoreszcens fehérjéket termelnek, így lehetővé teszik a mérgező anyagok ...
Bakos, Katalin +2 more
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