Results 51 to 60 of about 389,483 (184)

Five‐Year Treatment Outcomes of Macular Oedema Secondary to Central Retinal Vein Occlusion in Routine Clinical Practice: The Fight Retinal Blindness! Registry

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background To report 5‐year outcomes in a cohort of patients who received anti‐VEGF therapy for macular oedema secondary to central retinal vein occlusion (CRVO) in routine clinical practice. Methods In this retrospective observational study, 593 treatment‐naïve eyes that commenced anti‐VEGF treatment between 1 January 2010, and 2019 were ...
Katrin Rudolph, Marianna Rosso, Mark Gillies, Adrian Hunt, Louise O'Toole, Alessandro Invernizzi, David Squirrell, Hemal Mehta, Richard Barry, Pierre‐Henry Gabrielle, Daniel Barthelmes   +10 more
wiley   +1 more source

Multimodal Exploratory Analysis of Persistent Diabetic Macular Edema: Integrating Aqueous Humour Metabolomics, Clinical and OCT Features

Diabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11632-11642, December 2026.
ABSTRACT Purpose This exploratory study integrates aqueous humour metabolomic data with clinical and imaging features to examine candidate biomarkers and characterize multimodal patterns associated with persistent diabetic macular edema (pDME). Methods In this prospective cohort study, DME patients were treated with monthly anti‐VEGF injections over 3 ...
Yunhan Tao, Huimin Yu, Yunxi Ma, Mingzhu Yuan, Guochong Chen, Jun Liu, Xi Chen, Xufang Sun   +7 more
wiley   +1 more source

Ten Years of Severe Vitreomacular Traction Syndrome without Functional Damage Demonstrated by Optical Coherence Tomography

Case Reports in Ophthalmological Medicine, 2011
Introduction. To describe anatomical and functional features in one patient with 10 years of severe vitreomacular traction syndrome (VTS) without functional damage demonstrated by optical coherence tomography (OCT). Patient and Methods.
Michele Reibaldi, Teresio Avitabile, Maurizio Giacinto Uva, Francesco Occhipinti, Mario Toro, Marco Zagari, Andrea Russo   +6 more
doaj   +1 more source

Incomplete Vitreomacular Traction Release Using Intravitreal Ocriplasmin

Case Reports in Ophthalmology, 2014
Purpose: To report the clinical course of our first 7 consecutive patients treated with intravitreal ocriplasmin (Jetrea®). Methods: Retrospective case series of the first 7 patients treated with ocriplasmin between January and December 2013 at an ...
Eric K. Chin, David R.P. Almeida, Elliott H. Sohn, H. Culver Boldt, Vinit B. Mahajan, Karen M. Gehrs, Stephen R. Russell, James C. Folk   +7 more
doaj   +1 more source

Insights into the modulation of age‐related macular degeneration: Molecular and systems‐level perspectives

Acta Ophthalmologica, Volume 104, Issue S293, Page S4-S35, October 2026.
ENGLISH SUMMARY In developed countries, age‐related macular degeneration (AMD) is the leading cause of visual impairment in the aging population. Understanding of its pathogenesis is limited and the number of patients is predicted to continue rising. AMD is classified into two main forms: dry and neovascular AMD (dAMD and nAMD, respectively).
Hanna Heloterä
wiley   +1 more source

Characterising PRPF31‐associated retinal dystrophy: Clinical insights from baseline data in a natural history study

Acta Ophthalmologica, Volume 104, Issue 3, Page e317-e328, May 2026.
Abstract Purpose To characterise the baseline clinical features and genotypes of adults with pre‐mRNA processing factor 31 (PRPF31)‐associated retinal dystrophy (RD) enrolled in a prospective, multicentre 4‐year natural history study, and to explore correlations between selected baseline parameters.
Kathrine Olaussen Eriksen, Jon Roger Eidet, Ulrika Kjellström, Jacopo Baldesi, Ragnheidur Bragadóttir, Leonardo Colombo, Josephine Prener Holtan   +6 more
wiley   +1 more source

DELP Treatment on Vision and Retinal Microcirculation in Patients With Acute Ischemic Stroke: Report of Five Cases and Literature Review

Therapeutic Apheresis and Dialysis, Volume 30, Issue 2, Page 168-175, April 2026.
ABSTRACT Background The delipid extracorporeal lipoprotein filter from plasma (DELP) treatment can effectively reduce blood lipid, increase blood flow, and improve neurological deficits in patients with acute ischemic stroke (AIS). However, its effect on vision and retinal microcirculation in stroke patients has never been reported.
Ning Li, Ronghua Hong, Hua You, Feiping Xu, Qingjun Zhang, Yiwen Lin, Yuting Su, Danmei Lan, Lingjing Jin, Junhui She   +9 more
wiley   +1 more source

Mutational Analysis of Ocriplasmin to Reduce Proteolytic and Autolytic Activity in Pichia pastoris

Biological Procedures Online, 2020
Background Ocriplasmin (Jetrea) is using for the treatment of symptomatic vitreomacular adhesion. This enzyme undergoes rapid inactivation and limited activity duration as a result of its autolytic nature after injection within the eye.
Roghayyeh Baghban, Safar Farajnia, Younes Ghasemi, Reyhaneh Hoseinpoor, Azam Safary, Mojtaba Mortazavi, Nosratollah Zarghami   +6 more
doaj   +1 more source

A Case of Knobloch Syndrome With Lens Dislocation Resembling Homocystinuria

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT We report a 39‐year‐old woman with lifelong visual impairment who presented in June 2024 with progressive visual deterioration in her right eye. Ophthalmologic evaluation revealed severe high myopia, vitreoretinal degeneration, phthisis bulbi of the left eye, and downward lens dislocation of the right eye.
Elnaz Asadollahzadeh, Ali Rezaei, Vahid Shahmaei, Mohammad‐Sadegh Johari, Mohammad Ali Sahraian   +4 more
wiley   +1 more source

SD‐OCT‐based biomarkers in predicting treatment outcomes of macular oedema secondary to retinal vein occlusion treated with anti‐VEGF therapy

Acta Ophthalmologica, Volume 104, Issue 2, Page e152-e164, March 2026.
Abstract Purpose To investigate the role of spectral domain optical coherence tomography (SD‐OCT)‐based biomarkers in predicting treatment response of macular oedema (MO) secondary to retinal vein occlusion (RVO) to anti‐vascular endothelial growth factor (VEGF) therapy.
Ken K. Tsang, Vivian W. K. Hui, Christopher M. K. Pang, Ziqi Tang, Dawei Yang, Truong X. Nguyen, Shaheeda Mohamed, Timothy Y. Y. Lai, Carol Y. Cheung, Simon K. H. Szeto   +9 more
wiley   +1 more source