Results 151 to 160 of about 377,437 (162)

Translational and clinical advancements in management of proliferative vitreoretinopathy

Current Opinion in Ophthalmology, 2022
Purpose of review Despite advancement in the surgical instrumentation and techniques, proliferative vitreoretinopathy (PVR) remains the most common cause for failure of rhegmatogenous retinal detachment (RRD) repair.
A. Shahlaee, C. Woeller, N. Philp, Ajay E. Kuriyan   +3 more
semanticscholar   +1 more source

Molecular Targets for Proliferative Vitreoretinopathy

Seminars in Ophthalmology, 2021
While innovations in the surgical management of retinal detachment (RD) with proliferative vitreoretinopathy (PVR) have significantly improved anatomic and visual outcomes over the years, recurrent RD due to PVR remains the major limitation to success ...
Frances Wu, D. Eliott
semanticscholar   +1 more source

Vitreoschisis and retinal detachment: New insight in proliferative vitreoretinopathy

European Journal of Ophthalmology, 2021
Purpose To assess the occurrence of peripheral vitreoschisis-induced vitreous cortex remnants (p-VCRs) in primary rhegmatogenous retinal detachment (RD) and investigate whether the presence of p-VCRs results in a greater risk of RD recurrence, secondary ...
S. Rizzo, Lorenzo de Angelis, F. Barca, D. Bacherini, L. Vannozzi, F. Giansanti, F. Faraldi, T. Caporossi   +7 more
semanticscholar   +1 more source

STRUCTURAL AND FUNCTIONAL MACULAR CHANGES AFTER RETINECTOMY FOR RETINAL DETACHMENT COMPLICATED BY PROLIFERATIVE VITREORETINOPATHY

Retina, 2021
Satisfactory anatomical and functional outcome is possible after nonprimary retinectomy for retinal redetachment with proliferative vitreoretinopathy.
Piergiacomo Grassi, S. Melville, Anu-Sree Hariprasad, S. Winder, Y. Ramkissoon, Kurt Spiteri-Cornish, Raquel Garcia Cabrera, Siddharth Subramani, Anand Chawla   +8 more
semanticscholar   +1 more source

Intra-silicone Oil Injection of Methotrexate in Retinal Reattachment Surgery for Proliferative Vitreoretinopathy

Ocular immunology and inflammation, 2020
Purpose: To evaluate the role of intrasilicone oil injection of methotrexate (MTX) at the end of vitrectomy surgery for rhegmatogenous retinal detachment (RRD) associated with proliferative vitreoretinopathy (PVR).
K. Falavarjani, Ali Hadavandkhani, M. Parvaresh, M. Modarres, M. Naseripour, S. Alemzadeh   +5 more
semanticscholar   +1 more source

Self-assembling Hydrogel Loaded with 5-FU PLGA Microspheres as A Novel Vitreous Substitute for Proliferative Vitreoretinopathy.

Journal of Biomedical Materials Research. Part A, 2020
The vitreous substitute for proliferative vitreoretinopathy (PVR) surgery remains an unmet clinical need in ophthalmology. In our study, we developed an in situ formed hydrogel by crosslinking polyvinyl alcohol (PVA) and chitosan as a potential vitreous ...
Zhen Yu, Shisi Ma, Mengfan Wu, H. Cui, Rong Wu, Sizhe Chen, Chenlin Xu, Xiaohe Lu, Songfu Feng   +8 more
semanticscholar   +1 more source

Melatonin attenuates epidermal growth factor‐induced cathepsin S expression in ARPE‐19 cells: Implications for proliferative vitreoretinopathy

Journal of Pineal Research, 2020
Abnormal proliferation and motility of retinal pigment epithelial cells leads to proliferative vitreoretinopathy (PVR). Melatonin is a known effective antitumour and anti‐invasive agent, but whether it affects the formation and underlying mechanisms of ...
Shun-Fa Yang, Yong-Syuan Chen, Hsiang-Wen Chien, Kai Wang, Chia-Liang Lin, H. Chiou, Chia-Yi Lee, Pei-Ni Chen, Y. Hsieh   +8 more
semanticscholar   +1 more source

Comparison of Surgically Excised Premacular Membranes in Eyes with Macular Pucker and Proliferative Vitreoretinopathy

Current Eye Research, 2019
Purpose: To describe and compare characteristics of premacular membranes in idiopathic macular pucker (iMP) and proliferative vitreoretinopathy (PVR) using immunofluorescence and transmission electron microscopy.
S. Guenther, R. Schumann, F. Hagenau, A. Wolf, S. Priglinger, D. Vogt   +5 more
semanticscholar   +1 more source

Repeated Injection of Methotrexate into Silicone Oil-Filled Eyes for Grade C Proliferative Vitreoretinopathy: A Pilot Study

Ophthalmologica, 2019
Purpose: To evaluate the effects of repeated intra-silicone oil (SO) injections of methotrexate (MTX) on the outcomes of surgery for rhegmatogenous retinal detachment (RRD) with grade C proliferative vitreoretinopathy (PVR-C).
R. Nourinia, F. Borna, A. Rahimi, Mohammad Hossein Jabbarpoor Bonyadi, Y. Amizadeh, Arash Daneshtalab, B. Kheiri, H. Ahmadieh   +7 more
semanticscholar   +1 more source

BMP7 antagonizes proliferative vitreoretinopathy through retinal pigment epithelial fibrosis in vivo and in vitro

The FASEB Journal, 2018
The major pathogenesis of proliferative vitreoretinopathy (PVR) is that retinal pigment epithelial (RPE) cells undergo epithelial‐mesenchymal transition (EMT) because of disordered growth factors, such as TGF‐β, in the vitreous humor.
Haipei Yao, Tandi Ge, Yao Zhang, Min Li, Shuai Yang, Hui Li, F. Wang   +6 more
semanticscholar   +1 more source