Results 181 to 190 of about 4,584,652 (321)

Optimization and Validation of a High‐Performance Liquid Chromatography (HPLC‐UV) Method for Quantification of α‐Lipoic Acid in Cyclodextrins Complex for Ocular Delivery

open access: yesBiomedical Chromatography, Volume 39, Issue 7, July 2025.
ABSTRACT Alpha‐lipoic acid (ALA) is a natural antioxidant with therapeutic potential, but no method currently quantifies ALA in ocular structures. This study utilizes beta‐cyclodextrins (β‐CD) and (2‐hydroxypropyl)‐β‐cyclodextrins (HP‐β‐CD) to enhance ALA solubility and stability in 1:1 M ratio.
Phuong Linh Ta   +5 more
wiley   +1 more source

Targeting Connexin 43 in Retinal Astrocytes Promotes Neuronal Survival in Glaucomatous Injury

open access: yesGlia, Volume 73, Issue 7, Page 1398-1419, July 2025.
Main Points Astrocytes play an important role in glaucoma. These cells express Cx43 which can form gap junctions and hemichannels. This study shows Cx43 deletion in astrocytes provides neuroprotection in glaucoma, possibly through hemichannel activation.
Khulan Batsuuri   +4 more
wiley   +1 more source

Potassium‐Dependent Coupling of Retinal Astrocyte Light Response to Müller Glia

open access: yesGlia, Volume 73, Issue 7, Page 1520-1534, July 2025.
Main Points Astrocytes depolarize to light ON and OFF like Müller glia. The astrocyte light response is due to potassium influx. Retinal macroglial current‐voltage responses exhibit rectification which changes with repeated stimulation. ABSTRACT Astrocytes throughout the central nervous system mediate a variety of functions to support proper tissue ...
Joseph Matthew Holden   +3 more
wiley   +1 more source

Improving impact resistance of ceramic materials by energy absorbing surface layers [PDF]

open access: yes
Energy absorbing surface layers were used to improve the impact resistance of silicon nitride and silicon carbide ceramics. Low elastic modulus materials were used.
Kirchner, H. P., Seretsky, J.
core   +1 more source

Endoplasmic Reticulum Stress in Cancer

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Persistent ER stress in tumors activates UPR sensors (IRE1α, PERK, ATF6), driving cancer proliferation, metastasis, immune evasion, and drug resistance. This review explores UPR‐mediated signaling crosstalk, angiogenesis, and therapeutic targeting to develop safer anticancer strategies.
Ruixin Zhou   +5 more
wiley   +1 more source

Field efficacy of a bioherbicide mimic (DiS‐NH2) in a nanoparticle formulation for weed control in durum wheat

open access: yesPest Management Science, Volume 81, Issue 7, Page 3796-3810, July 2025.
A new polymeric nanoparticle formulation containing aminophenoxazinone DiS‐NH2 (2,2′‐disulfanediyldianiline) is proposed as a post‐emergence and contact bioherbicide for weed management in durum wheat. Abstract BACKGROUND Weed‐resistance phenomena have increased dramatically in recent years. Bioherbicides can offer a sustainable alternative to chemical
Aurelio Scavo   +7 more
wiley   +1 more source

Clinical Features of Seven COL2A1 Variations in Chinese Children With Type II Collagen Disorders

open access: yesActa Paediatrica, Volume 114, Issue 7, Page 1720-1730, July 2025.
ABSTRACT Aim Type II collagen, encoded by the collagen type II alpha 1 (COL2A1) gene, is crucial for the structure of cartilage. This study aims to improve our understanding of Spondyloepiphyseal Dysplasia Congenita (SEDC) caused by mutations in COL2A1. We also aim to evaluate the safety and efficacy of growth hormone (GH) therapy in two SEDC patients.
Shumin Zhan   +8 more
wiley   +1 more source

Embryonic Synthesis of the Inner Limiting Membrane and Vitreous Body

open access: green, 2005
Willi Halfter   +5 more
openalex   +3 more sources

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