Results 41 to 50 of about 4,584,652 (321)

Advances in Polysaccharide- and Synthetic Polymer-Based Vitreous Substitutes

open access: yesPharmaceutics, 2023
The vitreous humour is a gel-like structure that composes the majority of each eye. It functions to provide passage of light, be a viscoelastic dampener, and hold the retina in place.
Kruti Naik   +3 more
doaj   +1 more source

Intraocular Metallic Foreign Body: Role of Computed Tomography [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Orbital foreign bodies remain a serious diagnostic problem, despite development of diagnostic imaging techniques. Non-metallic orbital foreign body will not be detected in routine x-ray.
Suthar Pokhraj P.   +3 more
doaj   +1 more source

Elevated vitreous body glial fibrillary acidic protein in retinal diseases. [PDF]

open access: yesGraefes Arch Clin Exp Ophthalmol, 2015
PurposeIncreased expression of glial fibrillary acidic protein (GFAP) is a characteristic of gliotic activation (Müller cells and astrocytes) in the retina.
Jünemann AG   +8 more
europepmc   +2 more sources

Effects of lens extirpation with anterior vitrectomy on vitreous three-dimensional mesh structure [PDF]

open access: yesInternational Journal of Ophthalmology, 2017
AIM: To investigate the changes in vitreous gel structure after lens extirpation combined with anterior vitrectomy in rabbit eyes. METHODS: Twenty-eight chinchilla rabbits were divided into three groups. The control group (Group I) included 16 eyes from
Yan Zhao, Long-Fang Zhou, Hong Yang
doaj   +1 more source

A metabolomic approach to animal vitreous humor topographical composition: A pilot study [PDF]

open access: yes, 2014
The purpose of this study was to evaluate the feasibility of a 1H-NMR-based metabolomic approach to explore the metabolomic signature of different topographical areas of vitreous humor (VH) in an animal model.
ATZORI, LUIGI   +8 more
core   +1 more source

Postmortem tissue distribution of morphine and its metabolites in a series of heroin related deaths [PDF]

open access: yes, 2018
The abuse of heroin (diamorphine) and heroin deaths are growing around the world. The interpretation of the toxicological results from suspected heroin deaths is notoriously difficult especially in cases where there may be limited samples.
Beer, Lewis J.   +6 more
core   +4 more sources

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

Retinal tear formation after whole-body vibration training exercise

open access: yesBMC Ophthalmology, 2020
Background The purpose of this report is to describe the occurrence of a retinal tear, pre-retinal and vitreous hemorrhages after completing a session of whole-body vibration training.
John Maggiano   +4 more
doaj   +1 more source

Pharmacokinetics, Safety, and Efficacy of Intravitreal Digoxin in Preclinical Models for Retinoblastoma [PDF]

open access: yes, 2015
PURPOSE:To assess in vitro cytotoxic activity and antiangiogenic effect, ocular and systemic disposition, and toxicity of digoxin in rabbits after intravitreal injection as a potential candidate for retinoblastoma treatment.METHODS:A panel of two ...
Abramson, David   +13 more
core   +2 more sources

Proteomic analysis of the bovine and human ciliary zonule [PDF]

open access: yes, 2016
PURPOSE: The zonule of Zinn (ciliary zonule) is a system of fibers that centers the crystalline lens on the optical axis of the eye. Mutations in zonule components underlie syndromic conditions associated with a broad range of ocular pathologies ...
Bassnett, Steven   +3 more
core   +2 more sources

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