Results 41 to 50 of about 39,767 (221)

A Novel Slit Lamp‐Based System for 3D Ultrasound of the Eye

Journal of Ultrasound in Medicine, EarlyView.
Objectives This study aims to develop and evaluate a novel slit‐lamp‐based system to acquire 3‐dimensional (3D) ultrasound volumes using conventional ultrasound probes. Methods A slit‐lamp adapter was 3D printed and connected with a linear actuator and graphical user interface (GUI) system to control movement and create volumes of 2‐dimensional scans ...
Claire E. Malley, Joseph P. Miller, Boyan Pan, Josiah K. To, Jack O. Thomas, Steven Y. Chang, Jason Dagoon, William C. Tang, Parsa Riazi Esfahani, Andrew W. Browne   +9 more
wiley   +1 more source

Pathogenetic Aspects of the Development and Course of Rhegmatogenous Retinal Detachment against the Background of Proliferative Vitreoretinopathy. Literature Review

Oftalʹmologiâ, 2023
Retinal detachment (RD) is the most serious problem of modern ophthalmology, often leading to a decrease or irreversible loss of visual functions. The literature review is devoted to the latest trends in the study of the mechanisms of development and ...
J. V. Kudryavtseva, A. N. Semyonov
doaj   +1 more source

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li, Xue Wang, Wei Du, Qian Li, Hong‐Ping Cui   +4 more
wiley   +1 more source

VITREOUS BODY STRUCTURES INVESTIGATION USING THE «VITREOCONTRAST» SUSPENSION

Офтальмохирургия, 2015
Purpose. To develop a new method of vitreous body (VB) preparation with the isolate contrasting and separation of the VB structures (canals, cisterns, and their anastomosis).Material and methods. The research was performed in 20 cadaver donor eyes.
N. M. Kislitsyna, S. V. Novikov, A. V. Shatskikh, S. V. Kolesnik   +3 more
doaj  

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu, Xiao‐Bo Wan, Yong‐Shun Liang, Tian Lan, Hao Liang   +4 more
wiley   +1 more source

Vitreous body structures investigation using the «Vitreocontrast» suspension

Офтальмохирургия, 2013
Purpose. To develop a new method of vitreous body (VB) preparation with the isolate contrasting and separation of the VB structures (canals, cisterns, and their anastomosis). Material and methods.
N.M. Kislitsyna, S.V. Novikov, A.V. Shatskikh, S.V. Kolesnik   +3 more
doaj  

Ex Vivo Evaluation of Poly(Solketal Acrylate) Nanoparticles for Intravitreal Drug Delivery to the Posterior Eye Segment

Macromolecular Rapid Communications, EarlyView.
Nile Red‐loaded poly(solketal acrylate) nanoparticles enable fluorescence tracking and exhibit nontoxic profiles in retinal cells. Enhanced cellular uptake and deep retinal penetration after intravitreal injection highlight their excellent potential for targeted ocular drug delivery to the posterior segment of the eye.
Yasaman Pourdakheli Hamedani, José Hurst, Malte Ritter, Philipp Weingarten, Julia Skokowa, Sven Schnichels, Friederike Adams   +6 more
wiley   +1 more source

Microbiological study on foreign body and vitreous samples of patients with intraocular foreign body

Journal of International Medical Research, 2022
Objective To evaluate the relationship between the microbiological results of the vitreous humor and those of foreign body specimens in patients with intraocular foreign body (IOFB).
Seyed Ali Tabatabaei, Kazhaal Sheikhi, Reza Ghaffari, Mohammad Soleimani, Mansoor Shahriari, Kosar Esmaili, Sara Hobaby, Kasra Cheraqpour   +7 more
doaj   +1 more source

Presence of Nationally Banned Carbamates and Organophosphate Pesticides in Wild Carnivores, Southeastern Brazil

Environmental Toxicology, EarlyView.
ABSTRACT As top predators, terrestrial carnivores face great risk of pesticide exposure and serve as sentinels of environmental contamination. Additionally, terrestrial carnivores are frequently threatened by intentional or secondary poisoning with highly toxic compounds, such as carbamates and organophosphates.
Marina Pellegrino da Silva, Vagner Gonçalves‐Junior, Mauricio Candido da Silva, André Rinaldi Fukushima, Rose Lilian Gasparini‐Morato, Helenice de Souza Spinosa, Ana Carolina Ewbank, Carlos Sacristán, Ana de la Torre, José Luiz Catão‐Dias, Pedro Enrique Navas‐Suárez   +10 more
wiley   +1 more source

Randomized, single‐centre, double‐blinded repeated dose investigation of safety and tolerability of ocular administrations of a novel silica eye drop product in healthy volunteers

Acta Ophthalmologica, EarlyView.
Abstract Purpose Managing ocular diseases often requires frequent eye drop administration, which can challenge patient compliance. A long‐acting eye drop technology using an amorphous synthetic silica composite was developed to address this. Our study aimed to assess the safety and tolerability of the Silica Eye Drop platform in healthy volunteers over
Aleksandra Poluianova, Marceline N. Akieh‐Pirkanniemi, Arto Hartikainen, Hanna Arstila, Kai Kaarniranta, Lasse Leino   +5 more
wiley   +1 more source