Results 151 to 160 of about 1,445 (233)

Competent Non‐Native Alternative Host Reduces Infection Success in a Generalist Parasite

Ecology and Evolution, Volume 16, Issue 6, June 2026.
In this study, we experimentally assessed how the addition of a non‐native alternative host affects the infection success of the larval generalist trematode, Diplostomum pseudospathaceum, in fish intermediate hosts. Our results demonstrate that the presence of alternative hosts, especially the non‐native ones, can reduce parasite transmission through ...
Markéta Ondračková, Lukáš Vetešník, Veronika Bartáková, Michal Janáč   +3 more
wiley   +1 more source

DualPath‐DRNet: A Self‐Annotating Dual‐Path Networks for End‐To‐End Diabetic Retinopathy Diagnosis

Engineering Reports, Volume 8, Issue 6, June 2026.
DualPath‐DRNet for automated diabetic retinopathy diagnosis and grading. ABSTRACT One of the challenges in detecting Diabetic Retinopathy (DR) is the detection of subtle early‐stage microaneurysms. DualPath‐DRNet is an end‐to‐end deep learning pipeline for 5‐class DR prediction. The novelty of this method lies in combining lesion detection using YOLOv8,
Ankur Chaudhary, Neetu Faujdar, Ghanshyam Singh   +2 more
wiley   +1 more source

Replacing the vitreous body with hydrogels: Rationale and strategies. [PDF]

Prog Retin Eye Res
Schulz A, Keskar M, Swindle-Reilly KE, Junge V, Parikh BH, Su X, Liu Z, Seah I.   +7 more
europepmc   +1 more source

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source

Smart Polymer‐Based Drug Delivery Systems for Managing Infective Conjunctivitis: Advances and Future Prospects

Nano Select, Volume 7, Issue 6, June 2026.
The introduction covers the background and significance of conjunctivitis. It continues with a review of etiology, epidemiology, and clinical manifestations. Diagnostic methods are described, followed by discussions on pathophysiology and classification. Current treatment strategies, preventive measures, and therapeutic challenges are analyzed.
Xia Linkang, Marwan Abdelmahmoud Abdelkarim Maki, Saad Tayyab, Sachin Thakur, Pankaj Kumar, Ritu Karwasra, Mahesh Harihar Behare, Nitin Sharma, Wan Hamirul Bahrin Wan Kamal, Oganeswary Kobi, Kushagra Khanna, Mogana Rajagopal   +11 more
wiley   +1 more source

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang, Ngasin Lam, Xiaoming Huang, Yang Jiao   +3 more
wiley   +1 more source

Dual-Crosslinked Betaine-Based Amphiphilic Hydrogel as a Promising Vitreous Substitute: Anti-Adhesion, Anti-Fouling, and Anti-Cell Proliferation. [PDF]

Adv Sci (Weinh)
Cai Y, Tan Y, Cao J, Zhou X, Li X, Li J, Liu C, Zhang Y, Li Y.   +8 more
europepmc   +1 more source

Cryo‐FIB Lift‐Out and Electron Tomography Workflow for Bacteria–Nanopillar Interface Imaging Under Native Conditions: Investigating Dragonfly Inspired Bactericidal Titanium Surfaces

Small Methods, Volume 10, Issue 11, 8 June 2026.
A correlative cryo‐microscopy workflow enables targeted extraction and cryo‐electron tomography of bacteria–nanopillar interfaces under fully hydrated, near‐native conditions. By overcoming limitations of conventional imaging, this approach allows direct structural interrogation of bacteria–nanostructure interactions in situ, providing a methodological
Chaturanga D. Bandara, Dominik Pinkas, Martina Zanova, Martin Uher, Judith Mantell, Bo Su, Angela H. Nobbs, Paul Verkade   +7 more
wiley   +1 more source

Methanol-Related Fatalities in Jeddah, Saudi Arabia: A 5-Year Post-Mortem Multi-Matrix Study. [PDF]

Toxics
Al-Asmari AI, Zarnoogi A, Alharbi H, Alghamdi A, Alsolami F, Alzahrani AE, Alahmadi SA, Alotaibi NH, Alboug KA, Alzahrani MA, Zughaibi TA.   +10 more
europepmc   +1 more source

RORA Targeting PRNP Modulates Age‐Related Cataract via Activation Oxidative Injury‐Induced Cellular Senescence and Apoptosis of Lens Epithelial Cells

Aging Cell, Volume 25, Issue 6, June 2026.
The molecular mechanisms of RORA targeting PRNP activate oxidative injury‐induced cellular senescence and apoptosis of lens epithelial cells. Current research confirms that the transcription factor RORA targets PRNP, exacerbating cellular senescence and apoptosis of LECs (Figure 7).
Yue Zou, Wanqian Li, Jiaojiao Zhang, Chao Cen, Wanqiu Zheng, Ruonan Li, Hong Cheng, Liang Liang, Juan Kang, Wenjuan Wan, Ke Hu, Shijie Zheng   +11 more
wiley   +1 more source