Results 21 to 30 of about 1,445 (233)

Rheological Properties and Age-Related Changes of the Human Vitreous Humor [PDF]

Frontiers in Bioengineering and Biotechnology, 2018
The vitreous humor is a fragile, transparent hydrogel situated between the lens and the retina, occupying 80% of the eye's volume. Due to its viscoelastic behavior, the vitreous serves as a mechanical damper for the eye, absorbing impacts, and protecting
Nguyen K. Tram, Katelyn E. Swindle-Reilly, Katelyn E. Swindle-Reilly, Katelyn E. Swindle-Reilly   +3 more
doaj   +2 more sources

Fluid vitreous substitutes in vitreo retinal surgery

Indian Journal of Ophthalmology, 1996
Advances in the surgical instrumentation and vitreoretinal techniques have allowed intraoperative reapproximation of retina to a more normal position. The use of intravitreally injected liquid materials (viscoelastic liquids, liquid perfluorocarbons and ...
Saxena Sandeep, Gopal Lingam
doaj   +1 more source

In Vitro Physicochemical and Pharmacokinetic Properties of Bevacizumab Dissolved in Silicone Oils Compared to Hydrogel-Substitutes and Porcine Vitreous Bodies [PDF]

Gels
Anti-VEGF agents, e.g., bevacizumab, are used in retinal surgery, while their interaction with silicone oils and novel hydrogels remains unclear. This study examines the in vitro pharmacokinetics of bevacizumab in silicone oil-filled eyes compared to ...
Maximilian Hammer, Jonathan Herth, Lorenz Herbster, Manuel Ben Böhmann, Marcel Muuss, Ramin Khoramnia, Alexander Scheuerle, Walter Mier, Sabrina Wohlfart, Gerd Uwe Auffarth, Philipp Uhl   +10 more
doaj   +2 more sources

Alginate- and Hyaluronic Acid-Based Hydrogels as Vitreous Substitutes: An In Vitro Evaluation. [PDF]

Transl Vis Sci Technol, 2020
Art. 34, 12 S.Purpose: To study alginate- and hyaluronic acid-based hydrogels in vitro as vitreous substitutes. Methods: Biopolymeric hydrogels based on high-molecular alginate (0.5% and 1.0%) and hyaluronic acid (1.0% and Healaflow) were compared with ...
Schulz A, Rickmann A, Wahl S, Germann A, Stanzel BV, Januschowski K, Szurman P.   +6 more
europepmc   +2 more sources

Novel Supramolecular Hydrogels as Artificial Vitreous Substitutes

Macromolecular Symposia, 2010
AbstractThe possibility of employing self‐healing gels as potential artificial vitreous substitutes is being explored. Advancement of traditional synthetic hydrogels as vitreous substitutes is hindered by their fragmentation upon injection into the vitreous cavity leading ultimately to inflammation. Preliminary work involved developing first generation
Lee-Wang, Hui Hui, Blakey, Idriss, Chirila, Traian V., Peng, Hui, Rasoul, Firas, Whittaker, Andrew K., Dargaville, Bronwin L.   +6 more
openaire   +3 more sources

Vitreous Substitutes as Drug Release Systems. [PDF]

Transl Vis Sci Technol, 2022
Vitreous substitutes are traditionally used to stabilize the retina after vitrectomy. In recent years, various approaches have been developed for using the vitreous substitute not only as a tamponade but also as a drug release system to tackle ocular diseases.
Schulz A, Szurman P.
europepmc   +3 more sources

Vitreous Substitutes. [PDF]

Expert Rev Ophthalmol, 2008
Modern vitreoretinal surgery is a young science. While tremendous developments have occurred in instrument design and technique since Machemer first described vitrectomy surgery in 1973[1], the application of advanced materials concepts to the development of intra-ocular compounds is a particularly exciting area of research. To date, the development of
Foster WJ.
europepmc   +4 more sources

Advances in biomaterials as a retinal patch for the repair of rhegmatogenous retinal detachment

Frontiers in Bioengineering and Biotechnology, 2022
Rhegmatogenous retinal detachment (RRD) is the most common retinological emergency that can cause blindness without surgical treatment. RRD occurs when liquefied vitreous accumulates between the neurosensory retina and the retinal pigment epithelium via ...
Chuanzhen Zheng, Dejia Wen, Kejia Xu, Xiaomin Zhang, Xinjun Ren, Xiaorong Li   +5 more
doaj   +1 more source

Studying the Interaction of Viteral Substitutes with the Surface of Acrylic Intraocular Lenses

Oftalʹmologiâ, 2023
Purpose of the study: In vitro to study the degree of adhesion of vitreous substitutes, such as silicone oil of various viscosities and perfluorodecalin (PFOS), to hydrophobic acrylic polymer IOLs and evaluate the interaction of vitreous substitutes with
M. A. Plakhotniy, A. G. Shichkova, O. S. Kuznetsova, A. V. Tereschenko, I. G. Trifanenkova, N. N. Yudina, N. M. Shilov   +6 more
doaj   +1 more source

Functionalized hydrogels in ophthalmic applications: Ocular inflammation, corneal injuries, vitreous substitutes and intravitreal injection

Materials & Design, 2022
With the prevalence of eye diseases, such as inflamed eyes, corneal injury, cataract, glaucoma, and retinal degenerative diseases, different clinical strategies have been developed, however, they still suffer from many inevitable drawbacks in practical ...
Qiaoyun Gong, Yue Zhao, Tianwei Qian, Haiyan Wang, Zuhao Li   +4 more
doaj   +1 more source