Results 181 to 190 of about 826,455 (315)

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

open access: yesAdvanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao   +36 more
wiley   +1 more source

Relationship Between Quadriceps Neuromuscular Activity and Knee Extensor Strength at Four Months After ACL Reconstruction in High-Level Young Athletes. [PDF]

open access: yesOrthop J Sports Med
Sengoku T   +9 more
europepmc   +1 more source

Induced Proprioceptor and Low‐Threshold Mechanoreceptor Neurons Derived from Human Pluripotent Stem Cells Exhibit Distinct Functional Mechanosensory Properties

open access: yesAdvanced Science, EarlyView.
This study describes derivation of two distinct mechanosensory subpopulations from human pluripotent stem cells using a transcription factor mediated approach. Of significance, functional interrogation of induced mechanosensory subtypes reveal their unique responses to mechanical stimulation in the absence of end‐organs.
Amy J. Hulme   +12 more
wiley   +1 more source

A multimodal data-based diagnostic model for predicting vestibular migraine: a retrospective study. [PDF]

open access: yesFront Neurol
Zhang S   +10 more
europepmc   +1 more source

Dynamic Modulation of OECT‐Based Inverters for In Situ Electrophysiological Monitoring

open access: yesAdvanced Science, EarlyView.
This work presents a dynamic gain modulation system for inverter‐based in situ electrophysiological monitoring, enabling long‐term stable signal amplification via real‐time driving voltage adjustment. Moreover, stretchable complementary circuits (inverters, NAND, and NOR gates) are achieved based on a flexible PET substrate and a hexagonal network ...
Guohong Hu   +7 more
wiley   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

open access: yesAdvanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo   +3 more
wiley   +1 more source

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