Results 51 to 60 of about 456,270 (290)
IEEE Access, 2020 With the continuous expansion of the scale of cloud datacenters, high energy consumption has become a problem. Virtual machine (VM) consolidation is an effective method of energy management, but overly aggressive consolidation has caused issues such as ...
Yifan Shao +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Task-Driven Virtual Machine Optimization Placement Model and Algorithm
Future InternetIn cloud data centers, determining how to balance the interests of the user and the cloud service provider is a challenging issue. In this study, a task-loading-oriented virtual machine (VM) optimization placement model and algorithm is proposed ...
Ran Yang +3 more
doaj +1 more source
A Logic Programming Approach to VM Placement
Proceedings of the 14th International Conference on Cloud Computing and Services SciencePlacing virtual machines so to minimize the number of used physical hosts is an utterly important problem in cloud computing and next-generation virtualized networks. This article proposes a declarative reasoning methodology, and its open-source prototype, including four heuristic strategies to tackle this problem.
Andreoli, Remo +4 more
openaire +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
VirtCO: Joint Coflow Scheduling and Virtual Machine Placement in Cloud Data Centers
Tsinghua Science and Technology, 2019 Cloud data centers, such as Amazon EC2, host myriad big data applications using Virtual Machines (VMs). As these applications are communication-intensive, optimizing network transfer between VMs is critical to the performance of these applications and ...
Dian Shen +3 more
doaj +1 more source
VM Consolidation Plan for Improving the Energy Efficiency of Cloud
Cybernetics and Information Technologies, 2021 Achieving energy-efficiency with minimal Service Level Agreement (SLA) violation constraint is a major challenge in cloud datacenters owing to financial and environmental concerns.
Satveer, Aswal Mahendra Singh
doaj +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
Jointly Optimized Placement of Application VM and VNF in NFV Based Data Center
IEEE AccessIn data centers, applications are typically deployed in a distributed manner across servers via Virtual Machines (VMs). In order to enhance the application security and performance, the data flows between VMs often traverse a particular set of ...
Dandan Qi, Ruijun Gu
doaj +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source