Results 81 to 90 of about 43,525 (332)

Adjuvant radiotherapy after radical cystectomy for patients with muscle invasive bladder cancer : a phase II trial [PDF]

open access: yes, 2017
Background: Neo-adjuvant chemotherapy followed by radical cystectomy with extended pelvic lymph node dissection is considered to be the treatment of choice for patients with muscle invasive bladder cancer (MIBC).
De Meerleer, Gert   +7 more
core   +1 more source

The β integrin modulates serotonin sensitivity via NPxY motifs to regulate egg laying and mechanosensation behaviors in Caenorhabditis elegans

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm   +7 more
wiley   +1 more source

Characterization of Vesicular Monoamine Transporter 2 and its role in Parkinson\u27s Disease Pathogenesis using Drosophila [PDF]

open access: yes, 2016
Parkinson’s disease (PD) is a progressive neurodegenerative disorder caused by the selective loss of the dopaminergic neurons in the Substantia nigra pars compacta region of the brain.
Tito, Antonio Joel, Jr., Zhang, Sheng
core   +1 more source

Disparities in Proton Radiation Utilization for HPV‐Associated Oropharyngeal Cancer Following TORS

open access: yesHead &Neck, EarlyView.
ABSTRACT Introduction Racial, socioeconomic, and geographic disparities in receipt of proton radiation have been reported. Whether disparities exist for oropharyngeal squamous cell carcinoma (OPSCC) is not well studied. Methods Patients with HPV‐associated OPSCC treated with transoral robotic surgery (TORS) and adjuvant radiation from 2016 to 2023 were
Jane Y. Tong   +4 more
wiley   +1 more source

Performance Comparison of Knowledge-Based Dose Prediction Techniques Based on Limited Patient Data. [PDF]

open access: yes, 2018
PurposeThe accuracy of dose prediction is essential for knowledge-based planning and automated planning techniques. We compare the dose prediction accuracy of 3 prediction methods including statistical voxel dose learning, spectral regression, and ...
Landers, Angelia   +4 more
core  

Whole breast and regional nodal irradiation in prone versus supine position in left sided breast cancer [PDF]

open access: yes, 2017
Background: Prone whole breast irradiation (WBI) leads to reduced heart and lung doses in breast cancer patients receiving adjuvant radiotherapy. In this feasibility trial, we investigated the prone position for whole breast + lymph node irradiation (WB +
A Berrington de Gonzalez   +56 more
core   +2 more sources

Dosimetric and clinical outcomes after volumetric modulated arc therapy for carcinoma of the thoracic esophagus

open access: yesAdvances in Radiation Oncology, 2017
Purpose: The efficiency of radiation delivery via volumetric modulated arc therapy (VMAT) is indisputable, but outcomes after VMAT for thoracic esophageal carcinoma are largely unknown.
Cai Xu, MD   +7 more
doaj   +1 more source

Dosimetric Comparison of Pelvic Bone Marrow Preservation between Volumetric-Modulated Arc Therapy and Intensity-Modulated Radiotherapy in Radical Radiotherapy of High-Risk Prostate Cancer [PDF]

open access: yesResearch in Oncology, 2019
Background: Pelvic bone marrow (PBM) preservation is one of the factors that should be taken into consideration while choosing a technique for radiotherapy of pelvic malignancies.
Ehab Saad   +2 more
doaj   +1 more source

Optimizing the integration of modern systemic therapies and advanced radiotherapy techniques in breast cancer management: An expert opinion from the Institut Curie Breast Radiotherapy Group

open access: yesInternational Journal of Cancer, EarlyView.
Abstract The integration of modern systemic therapies with radiotherapy (RT) represents a promising strategy in breast cancer management, enhancing both locoregional control and systemic disease outcomes. This expert consensus from the Institut Curie Breast Radiotherapy Group focuses exclusively on modern systemic agents, synthesizing current evidence ...
Cezara Cheptea   +5 more
wiley   +1 more source

Searching standard parameters for volumetric modulated arc therapy (VMAT) of prostate cancer [PDF]

open access: yes, 2012
Background Since December 2009 a new VMAT planning system tool is available in Oncentra® MasterPlan v3.3 (Nucletron B.V.). The purpose of this study was to work out standard parameters for the optimization of prostate cancer.
Dobler, Barbara   +3 more
core   +2 more sources

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