Results 81 to 90 of about 29,307 (243)

A Feasibility Study of the Repurposing of Prazosin to Improve Treatment Outcomes in Men Receiving Radiotherapy for Prostate Cancer (MiniRaP‐00)

The Prostate, EarlyView.
ABSTRACT Background Further work is needed to improve treatment outcomes for prostate cancer (PCa), with the repurposing of the α1‐adrenoreceptor antagonists presenting a potential solution. This feasibility clinical trial presents the first prospective data of the use of an α1‐adrenoreceptor antagonist in men undergoing radiotherapy for PCa.
Liam D. King, David Christie, Daniel Cehic, Wendy Dare, Russ Chess‐Williams, Donna Sellers, Catherine McDermott, Alexandra McCarthy, Shailendra Anoopkumar‐Dukie   +8 more
wiley   +1 more source

Multi-GPU implementation of a VMAT treatment plan optimization algorithm

, 2015
VMAT optimization is a computationally challenging problem due to its large data size, high degrees of freedom, and many hardware constraints. High-performance graphics processing units have been used to speed up the computations.
Folkerts, Michael, Jia, Xun, Jiang, Steve B., Peng, Fei, Tan, Jun, Tian, Zhen   +5 more
core   +1 more source

Patterns of CT lung injury and toxicity after stereotactic radiotherapy delivered with helical tomotherapy in early stage medically inoperable NSCLC [PDF]

, 2015
To evaluate toxicity and patterns of radiologic lung injury on CT images after hypofractionated image-guided stereotactic body radiotherapy (SBRT) delivered with helical tomotherapy (HT) in medically early stage inoperable non-small-cell lung cancer ...
Agolli, Linda, Arcangeli, S, Bracci, S, Dognini, Jessica, Donato, Vittorio, Lopergolo, M. G, Migliorino, M. R, Monaco, Alessia, Portalone, L, Pressello, M. C   +9 more
core   +1 more source

Dopamine: The Essential Bridge Mediating Obstructive Sleep Apnea and Hippocampus‐Dependent Learning and Memory Impairments

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Obstructive sleep apnea is a clinical syndrome that triggers a series of pathophysiologic changes, including disturbed sleep architecture, chronic intermittent hypoxia and hypercapnia, and ultimately severe cognitive dysfunction. The hippocampus plays a key role in various cognitive processes such as learning and memory.
Rui Fan, Tao Li, Yan Yan
wiley   +1 more source

Dosimetric analysis of half-field-based VMAT with the deep inspiration breath-hold technique for left breast cancer patients following breast-conserving surgery

Frontiers in Oncology
ObjectiveCompared the dosimetric characteristics of half-field-based VMAT and half-field-based IMRT for left breast cancer patients combined with deep inspiration breath-hold (DIBH) and free breathing (FB) techniques.MethodsTwenty-one left breast cancer ...
Weiwei Wu, Hui Yin, Zhiwei Liu, Lipeng Liu, Chengjian Xiao, Ying Xiao, Jinquan Ding, Qungui Zhang, Hailiang Guo   +8 more
doaj   +1 more source

Differential regulation of the Drosophila sleep homeostat by circadian and arousal inputs. [PDF]

, 2019
One output arm of the sleep homeostat in Drosophila appears to be a group of neurons with projections to the dorsal fan-shaped body (dFB neurons) of the central complex in the brain.
Elsheikh, Ahmed, Gurav, Adishthi S, Hackbart, Hannah, Liu, Weiwei, Montell, Craig, Ni, Jinfei D, Ogunmowo, Tyler H, Verdegaal, Andrew A   +7 more
core   +1 more source

Comparison of breast simultaneous integrated boost (SIB) radiotherapy techniques [PDF]

, 2015
Purpose: To dosimetrically evaluate different breast SIB techniques with respect to target coverage and organs at risk (OARs) doses. Methods: Four IMRT techniques were compared in 12 patients. Three techniques employ tangential whole breast irradiation
Aly, Moamen M.O.M., Glatting, Gerhard, Jahnke, Lennart, Madyan, Yasser, Wenz, Frederik   +4 more
core   +1 more source

Automated contouring, treatment planning, and quality assurance for VMAT craniospinal irradiation (VMAT-CSI)

Frontiers in Oncology
PurposeCreate a comprehensive automated solution for pediatric and adult VMAT-CSI including contouring, planning, and plan check to reduce planning time and improve plan quality.MethodsSeventy-seven previously treated CSI patients (age, 2-67 years) were used for creation of an auto-contouring model to segment 25 organs at risk (OARs).
Eric Simiele, Ignacio O. Romero, Jen-Yeu Wang, Yizheng Chen, Yuliia Lozko, Yuliia Severyn, Lawrie Skinner, Yong Yang, Lei Xing, Iris Gibbs, Susan M. Hiniker, Nataliya Kovalchuk   +11 more
openaire   +3 more sources

Estimating the Carbon Footprint of External Beam Radiotherapy: Should This Be a Concern for LMICs?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Purpose This study aims to estimate the carbon footprint associated with external beam radiotherapy in a low‐ and middle‐income country (LMIC) context, specifically at the Uganda Cancer Institute (UCI), and to evaluate whether sustainability should be a priority alongside treatment access in such radiation therapy settings.
Afua A. Yorke, Komakech Ignatius, John L. Schreiner, Tomas Kron   +3 more
wiley   +1 more source

Deep learning-based upsampling of 2D detector array measurements for patient plan verification in radiotherapy. [PDF]

Med Phys
Abstract Background Detector arrays are commonly used for treatment plan verifications in intensity modulated radiation therapy. However, the intrinsic resolution of detector arrays is limited by the physical dimensions of each single detector and the detector‐to‐detector distance.
Pflaum A, Brand N, Kempf E, Weidner J, Eulenstein D, Delfs V, Poppe B, Looe HK.   +7 more
europepmc   +2 more sources