Results 91 to 100 of about 321,436 (291)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Vocations, Exploitation, and Professions in a Market Economy [PDF]
, 2018 In a market economy, members of professions—or at least those for whom their profession is a vocation—are vulnerable to a distinctive kind of objectionable exploitation, namely the exploitation of their vocational commitment.
Koltonski, Daniel
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Hyperspectral Image Denoising via Quasi-Recursive Spectral Attention and Cross-Layer Feature Fusion
SensorsHyperspectral images (HSIs) contain rich spatial–spectral information but are highly susceptible to various types of noise during the imaging process, which significantly degrades image quality and undermines the reliability of subsequent applications ...
Yanhua Xiao +4 more
doaj +1 more source
Reflexivity in Police Education
Nordisk Politiforskning, 2017 This interview study of Swedish police field-training officers (FTOs) and their conceptions of the task of mentoring and assessing police probationers exemplifies how a field-training task can be understood as a learning incentive for professional ...
Bengt Bergman
doaj +1 more source
Vocational Rehabilitation [PDF]
Journal of the Royal Society of Medicine, 2003 Andrew O, Frank, Philip, Sawney
openaire +2 more sources
Female-owned innovative startups in Italy: status quo and implications [PDF]
, 2018 The aim of the paper is to provide an overview of the current literature of this business phenomenon with regard to gender studies and to point out what is substantially happening and what has happened in the Italian economic context.
Modaffari, Giuseppe, Paoloni, Paola
core +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Depression and Contributors to Vocational Satisfaction in Roman Catholic Secular Clergy [PDF]
, 2005 A nationally selected, random sample of Roman Catholic secular (i.e., diocesan) priests was examined using the Center for Epidemiological Studies-Depression scale and an instrument developed for this study to assess contributors to priests’ vocational ...
Knox, Sarah +3 more
core +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source