Results 51 to 60 of about 75,656 (288)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
, 2008 This chapter examines the concept of religious vocation. In Christian history, vocation has become bound up with the category of work in three different ways. The chapter explains these three ways.
John G. Stackhouse
core +1 more source
Scientific ReportsThe rapid urbanization of cities has exacerbated traffic congestion, resulting in significant environmental impacts, including elevated greenhouse gas emissions and deteriorating air quality.
Ruokun Wang +4 more
doaj +1 more source
Swiss Journal of Sociology, 2017 This article draws on a long-term ethnographical survey. It aims to discuss the social conditions of possibility in the artistic calling of contemporary dancers from working class backgrounds.
Sorignet Pierre-Emmanuel
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Vocation of a Doctor [PDF]
The Linacre Quarterly, 2012 Doctors are called to a life of compassionate service to human beings invested with intrinsic dignity. This essay is adapted from the commencement address that Dr. Landry delivered at the St. Louis University School of Medicine on July 18, 2011.
openaire +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
, 2013 Qu’est-ce que la vocation à l’aube de l’époque moderne ? Issu du verbe vocare, le substantif latin vocatio signifie « appel ». Aussi la vocation a-t-elle pour sens premier l’appel à accomplir la volonté divine.
Edouard, Sylvène +4 more
core +1 more source
La correspondance de Jacques Rivière et Alain-Fournier : une aventure de la lecture
Itinéraires, 2010 Through a precise study of the letters that Jacques Rivière and Alain-Fournier wrote to each other between 1904 and 1909, when they were young men, the article uncovers a form of existential event in the very act of reading.
Julie Aucagne
doaj +1 more source