Results 101 to 110 of about 67,345 (239)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Eminescology – a Constant Concern of the Researcher Dumitru Apetri

open access: yesPhilologia
The article reveals the contribution of the scholar and writer Dumitru Apetri to Eminescian creation and Eminescology – masterful fields of Romanian philology.
Vlad CARAMAN
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

060. Vocation

open access: yes, 2008
Your vocation is more than your job it is your mask of God in service to state, church and home.https://scholar.csl.edu/christiandoctrine/1059/thumbnail ...
Biermann, Joel
core  

Vocation. Vocation.

open access: yes, 2016
I’m tendrils today. Speak to me, I’ll write a poem. Show me the bark, I’ll plant you a tree. Crash me skyblue, I’ll comfort you a cloud. Stand at the bus reading a novel, I’ll oratorio right back at you in a strange and distant land she stood like no ...
Bullock, Owen
core   +3 more sources

Boundaries and Relationships in Homelessness Work: Lola, an Agency Manager

open access: yesForum: Qualitative Social Research, 2004
The professional is also a human being. This paper explores the complementary and con­tra­dictory relation between biography and vocation in the history of a nurse who became a social work manager, as revealed in a biographic-narrative interview.
Tom Wengraf
doaj  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Vocation As Curse [PDF]

open access: yes, 1999
This Essay argues that while legal work as a vocation may have positive effects for society as a whole, as well as overall benefits for the legal profession, vocation could very well hurt the lawyer called to take up such a vocation. A vocation is not
Giba-Matthews, ofm, F.
core   +1 more source

Hohol’s Anthropological Project in the Russian Empire

open access: yesAntropologìčnì Vimìri Fìlosofsʹkih Doslìdžen'
Purpose. To reconstruct Hohol’s point of view on his anthropological project, that is, to identify his answers to the question of what a person is in the dimensions of the essential and the proper.
A. M. Malivskyi   +2 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

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