Results 81 to 90 of about 2,873 (215)
Eminescology – a Constant Concern of the Researcher Dumitru Apetri
PhilologiaThe article reveals the contribution of the scholar and writer Dumitru Apetri to Eminescian creation and Eminescology – masterful fields of Romanian philology.
Vlad CARAMAN
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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Boundaries and Relationships in Homelessness Work: Lola, an Agency Manager
Forum: Qualitative Social Research, 2004 The professional is also a human being. This paper explores the complementary and contradictory relation between biography and vocation in the history of a nurse who became a social work manager, as revealed in a biographic-narrative interview.
Tom Wengraf
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
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Vocational Rehabilitation [PDF]
Journal of the Royal Society of Medicine, 2003 Andrew O, Frank, Philip, Sawney
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Hohol’s Anthropological Project in the Russian Empire
Antropologìčnì Vimìri Fìlosofsʹkih Doslìdžen'Purpose. To reconstruct Hohol’s point of view on his anthropological project, that is, to identify his answers to the question of what a person is in the dimensions of the essential and the proper.
A. M. Malivskyi +2 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
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Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
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International Journal of Qualitative ResearchThis qualitative research aims to obtain data on the meaning of prayer for young Catholic religious of the Congregation of Blessed Virgin Mary of Amersfoort of Samarinda Province.
Carolus Borromeus Mulyatno +1 more
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Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
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