Results 51 to 60 of about 67,345 (239)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Platform Empowerment and Digital Inclusion in Industrial Clusters: A Complex Network Game Analysis with Performance Feedback

Games
The digital divide between large enterprises and SMEs (Small and Medium-sized Enterprises) within industrial clusters poses a significant challenge to achieving collective digital transformation, exacerbated by the quasi-public goods, attributes of ...
Dingteng Wang, Chengwei Liu, Shuping Wang   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Editors' Duty: Vocation or Profession?

, 2019
Editorial 2013-IIEditors' Duty: Vocation or ...
Rojas Galeano, Sergio Andrés
core   +1 more source

Multi-modal and multi-agent reinforcement learning framework for urban traffic flow prediction and signal control optimization

Scientific Reports
The rapid urbanization of cities has exacerbated traffic congestion, resulting in significant environmental impacts, including elevated greenhouse gas emissions and deteriorating air quality.
Ruokun Wang, Ju Zhang, Xikui Wang, Haoyang He, Yuelin Zou   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Summer religious vocation school, 1938

, 1938
Elementary school boys and Jesuit participants in summer religious vocation school<br>Verso caption: Vocation School, 1938 Student group photos, mixed ages, 1931 ...

core   +1 more source

“You’re Not a Real Contemporary Dancer.” Discrepancy and Appropriation of the Artists’ Status by Dancers from a Working Class Background

Swiss Journal of Sociology, 2017
This article draws on a long-term ethnographical survey. It aims to discuss the social conditions of possibility in the artistic calling of contemporary dancers from working class backgrounds.
Sorignet Pierre-Emmanuel
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The Vocation Learning Outcomes at the University of Dayton [PDF]

, 2016
In the Fall of 2015, the HIR Fellows for Vocation entered an exploration of the Vocation Learning Outcome outlined in the Habits of Inquiry and Reflection (2006), the document undergirding the development of the Common Academic Program.
Sullivan, Crystal, Dickey, Irene J., Schaller, Molly, Neiheisel, Steven, Kinnucan-Welsch, Kathryn, Kwon, Suki, MFA, Eckert, Jason, Wilhoit, Stephen, Wallace, Cari   +8 more
core