Results 71 to 80 of about 53,802 (311)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

‘Missed Vocation? The Failed Writer in Late Victorian Women’s Fiction.’

open access: yes, 2014
The difficulties of self-presentation for Victorian women writers, and the troubled history of their literary standing, have been well documented. To take just one example, Helen Black’s Ladies Pictorial interviews with Notable Women Authors of the Day ...
Oulton, C.
core  

The Poetic Vocation

open access: yes, 2021
This hybrid critical/creative essay discusses the vocation of being a poet and the attendant problems of earning a living. It describes the lure and attraction of writing poetry, employment history, barriers to the academic world and an eventual ...
Bullock, Owen
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Dental student’s satisfaction towards orthodontic laboratory work from RSGM Dental Laboratory

open access: yesDental Journal, 2015
Background: Customer satisfaction plays an important role in the success and continuity of a business. Dental Laboratory of RSGM Faculty of Dental Medicine Universitas Airlangga provides services for Faculty of Dental Medicine, Universitas Airlangga ...
Sianiwati Goenharto   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Suffering and the prophetic vocation

open access: yes, 2012
The "self-disclosures" in Jeremiah, including not only the so-called "confessions" but also other first person material which seems to express the prophet's inner feelings, are examined in a detailed, exegetical fashion with careful ...
Hayner, Stephen Allen
core  

Vocation\u27s Unbroken Chain: Biblical Call Stories and the Experience of Vocation

open access: yes, 2020
This essay reflects on the Biblical passages used to create a vocational curriculum produced by the author\u27s doctoral project. The call stories of Abraham, Joseph, Moses, and Ruth are examined to illustrate the experience of vocation.
Keeton, Chris
core   +1 more source

IN SEARCH OF ITS OWN IDENTITY: MASS-MEDIA IN POST-COMMUNISM [PDF]

open access: yesDiversitate si Identitate Culturala in Europa, 2014
The present research focuses on the mass-media system as it evolved in the first post-communist decade. Right after December 1989, hundreds of newspapers, magazines and other kinds of publications appeared in Romania.
Lucian CHIŞU
doaj  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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