Results 81 to 90 of about 53,802 (311)
, 2017 Le mot vocation ne saurait ici être pris dans son sens premier d’appel intérieur. C’est évidemment au terme de processus sociaux et exclusivement sociaux qu’un individu finit par considérer concevable, possible, souhaitable, de postuler au rôle de maire.
Le Bart, Christian
core +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
La formation ecclésiale au prisme d’une série TV : dé-singularisation d’un dispositif
Images du Travail, Travail des Images, 2018 In our society influenced by secularization, to become a priest in the XXIth century questions. This work deals with the representation of the priesthood training through the french TV series Ainsi soient-ils broadcasted from 2012 to 2015.
Benoît Verdier
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
, 1999 This Essay argues that while legal work as a vocation may have positive effects for society as a whole, as well as overall benefits for the legal profession, vocation could very well hurt the lawyer called to take up such a vocation. A vocation is not
Giba-Matthews, ofm, F.
core +1 more source
, 2008 Course Description This course addresses the question, How is a vocation to Christian ministry discerned, shaped, and sustained? The purpose of the course is to explore the foundations for Christian vocation by examining the connection between a call to ...
Harper, Steve
core +3 more sources
Teaching as Profession and Vocation
, 2002 Teaching understood as a profession sometimes conflicts with teaching understood as a Christian vocation. In order to see whether and why this claim is true, the essay first examines the present state of the conversation about the general idea of ...
Mark R. Schwehn
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source