Results 41 to 50 of about 1,359,849 (169)

Developing the biomarker panels and drugs by proteomic analysis for autoimmune uveitis and posterior scleritis

iScience
Summary: Autoimmune uveitis and posterior scleritis are ocular diseases caused by immune dysregulation. Their pathogenesis remains elusive, and delayed diagnosis can exacerbate vision loss.
Xueru Li, Jinying An, Lingzi Wu, Qingqin Tao, Hui Zhang, Xiaomin Zhang   +5 more
doaj   +1 more source

Vogt-Koyanagi-Harada syndrome presenting with encephalopathy

Annals of Indian Academy of Neurology, 2013
VogtKoyanagi-Harada (VKH) is a rare syndrome affecting tissues with melanocytes. The possibility that VKH syndrome has an autoimmune pathogenesis is supported by the high frequency of human leukocyte antigen-DR4 commonly associated with other autoimmune ...
Alireza E Naeini, Dana Daneshmand, Farzin Khorvash, Ahmad Chitsaz   +3 more
doaj   +1 more source

Females Display Greater Disease Severity in a Mouse Model of Vitiligo

Pigment Cell &Melanoma Research, Volume 39, Issue 6, November 2026.
We compared depigmentation in vitiligo‐prone, h3TA2 mice among males and females, and explored the effects of treatment with HSP70iQ435A plasmid DNA, delivered by biolistic administration. Mice shown from each cohort exemplify increased depigmentation among female mice and the treatment benefit of HSP70iQ435A. ABSTRACT Vitiligo is an autoimmune disease
Kaitlyn G. O'Donnell, Zhussipbek Mukhatayev, Hanin Abuzer, Rohan S. Shivde, Sriram Saravanan Shanmugavelandy, Octavio K. Bartos, Ellis Kang, Emilia R. Dellacecca, Dinesh Jaishankar, Surya Pandey, Hee Kap Kang, Ziyou Ren, I. Caroline Le Poole   +12 more
wiley   +1 more source

Vogt-Koyanagi-Harada Syndrome

, 2022
Vogt-Koyanagi-Harada (VKH) syndrome is a rare disorder that affects several body systems. Here we take a broad look at the presentation and pathophysiology of VKH, with a more specific focus on the relevant eye findings. Since much is not known about VKH,
Shwetha Mudalegundi, Medical Student; Amanda D. Henderson, MD
core  

Síndrome de Vogt-Koyanagi-Harada [PDF]

, 2016
El síndrome de Vogt-Koyanagi-Harada es una enfermedad con hallazgos dermatológicos, neurológicos y auditivos, asociada con una panuveítis granulomatosa bilateral.
Serna-Ojeda, Juan Carlos, Miguel Pedroza-Seres, Juan Carlos Serna-Ojeda, Pedroza-Seres, Miguel   +3 more
core   +1 more source

Bilateral serous retinal detachments associated with burkitt lymphoma

American Journal of Ophthalmology Case Reports, 2020
Purpose: To report a case of bilateral serous retinal detachments in a patient found to have burkitt lymphoma. Observations: A patient who presented with bilateral serous retinal detachments and “B” symptoms underwent extensive workup and was found to ...
Matthew S. Wieder, Jay A. Fleischman, Saadia Rashid   +2 more
doaj   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, Volume 13, Issue 59, 23 October 2026.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

Vogt-Koyanagi-Harada syndrome and keratoconjunctivitis sicca

, 2004
PURPOSE: To discover a relationship between Vogt-Koyanagi- Harada (VKH) syndrome and Sjogren syndrome. DESIGN: Observational case-control study. METHODS: Sixteen Italian patients with VKH syndrome and 16 controls with diffuse uveitis underwent tear ...
PRIORI R., DA DALT S., CORRADI R., PAROLI, Maria Pia, PIVETTI, Paola   +4 more
core   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Bilateral betrayal: When imaging calls out Vogt–Koyanagi–Harada’s one-eyed act

Indian Journal of Ophthalmology. Case Reports
We report a case of asymmetric Vogt-Koyanagi-Harada syndrome mimicking unilateral Central Serous Chorioretinopathy. This case highlights the diagnostic challenge for making a correct diagnosis between asymmetric Vogt-Koyanagi-Harada disease and Central ...
Shagun Korla, Gain C Rajput, Shreya Narang   +2 more
doaj   +1 more source