Results 31 to 40 of about 137,343 (204)

Macular Abnormalities in Vogt-Koyanagi-Harada Disease

, 2019
Purpose: To investigate the prevalence of macular abnormalities in Chinese Vogt-Koyanagi-Harada (VKH) patients. Methods: Clinical characteristics, therapeutic effectiveness and visual outcome were reviewed and analyzed.
Qingyun Zhou (391545), Aize Kijlstra (52532), Liping Du (301240), Jian Qi (345934), Zi Ye (302115), Jing Xu (15337), Liang Liang (19309), Chaokui Wang (351525), Chunjiang Zhou (5595575), Qingfeng Cao (561890), Lili Wu (559545), Peizeng Yang (42067)   +11 more
core   +2 more sources

Vogt-Koyanagi-Harada Syndrome in Two Patients with Immunoglobulin A Nephropathy [PDF]

, 2007
We describe herein 2 patients who developed Vogt-Koyanagi-Harada syndrome in the course of renal biopsy-proven immunoglobulin A (IgA) nephropathy. A 61-year-old man with an 11-year history of IgA nephropathy and a 16-year history of thyroiditis, and a 56-
Ota, Kosuke, Masuda, Ikuya, Nose, Soichiro, Sunami, Reiko, Yamadori, Ichiro, Matsuo, Toshihiko   +5 more
core   +1 more source

Hints from the skin beneath: Vitiligo in Vogt–Koyanagi–Harada disease

Dermatologica Sinica, 2022
Vogt–Koyanagi–Harada disease (VKHD) is a major vision-threatening autoimmune disease. One of its associated features is vitiligo. Little study has been done on the association between vitiligo and the disease activity of VKHD.
Jo Anne Lim, Wooi Chiang Tan, Norazirah Md Nor   +2 more
doaj   +1 more source

Sindrome de Vogt-Koyanagi-Harada: relato de dois casos

Arquivos de Neuro-Psiquiatria, 1981
Os autores relatam a síndrome de Vogt-Koyanagi-Harada em duas mulheres adultas e de cor parda. São discutidos os aspectos clínicos, epidemiológicos, heredofamiliares e imunológicos.
Paulo E. Marchiori, Milberto Scaff, Dagoberto Callegaro, Noboru Yassuda, José Lamartine De Assis   +4 more
doaj   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

A fingerprint hidden inside the eye. A unique pattern of outer retina splitting as seen on en-face OCT and OCT-angiography

American Journal of Ophthalmology Case Reports, 2021
A splitting of the outer plexiform retinal layer in a saw-like hyporeflective pattern in addition to partially formed concentric circles centred at the foveola were observed using en-face OCT and OCT-angiography in a 27-year-old female patient with ...
Tryfon Rotsos, Chrysanthos Symeonidis, Menelaos Kanakis, Konstantinos Andreanos   +3 more
doaj   +1 more source

Vogt-Koyanagi-Harada disease in children [PDF]

Eye, 2007
To identify prognostic factors for outcome in children with Vogt-Koyanagi-Harada (VKH) disease.All children 16 years and younger with acute uveitis associated with VKH disease treated between 1999 and 2006 were reviewed.Twenty-three children (46 eyes) were identified; 20 (87%) girls and three (13%) boys with a mean age at presentation of 12.5+/-2.4 ...
A M, Abu El-Asrar, A S, Al-Kharashi, H, Aldibhi, H, Al-Fraykh, D, Kangave   +4 more
openaire   +2 more sources

Novos conhecimentos sobre a doença de Vogt-Koyanagi-Harada [PDF]

, 2009
Vogt-Koyanagi-Harada disease (VKH), a well-established multiorgan disorder affecting pigmented structures, is an autoimmune disorder of melanocyte proteins in genetically susceptible individuals.
DAMICO, Francisco Max, BEZERRA, Felipe Theodoro, GASPARIN, Fábio, YAMAMOTO, Joyce Hisae, SILVA, Gaspar Carvalho da   +4 more
core   +1 more source

A case of recalcitrant pediatric Vogt-Koyanagi-Harada disease successfully controlled with adalimumab

Journal of the Formosan Medical Association, 2019
Vogt-Koyanagi-Harada (VKH) disease is uncommon in the pediatric population and can have an aggressive course with serious visual sequelae. A 12-year-old Han Chinese American female, who presented with mild headaches and panuveitis with diffuse serous ...
Emily Su, Vikash S. Oza, Paul Latkany
doaj   +1 more source

Upadacitinib Restrains the Pathogenic Fitness of CD4+ T Cells and Aberrant B Cell Programming in Optic Neuritis

Advanced Science, EarlyView.
Single‐cell profiling and functional perturbation reveal coordinated JAK1‐pSTAT3 downstream programs in optic neuritis, including MCL1‐dependent fitness of pathogenic CD4+ Tem cells and glycolysis‐linked, cholesterol‐sensitive B‐cell responses associated with RORA. Upadacitinib disrupts this reciprocal T‐B‐cell circuit and alleviates neuroinflammation,
Gengchen Jiang, Qi Jiang, Lian Han, Yue Peng, Xingyu Liu, Tong Yang, Hao Huang, Jiaying Liu, Yuan Gao, Hui Yang, Wenjun Zou, Zhaohuai Li, Wenru Su   +12 more
wiley   +1 more source