Results 21 to 30 of about 4,991,692 (213)

Vogt–Koyanagi–Harada Syndrome (VKHS): First Two Cases Reported in Pediatric Age Group in Oman

Case Reports in Pediatrics, 2023
The Vogt–Koyanagi–Harada syndrome (VKHS) is a unique form of granulomatous autoimmune disease that mostly impacts the pigmented tissues of the body. The main feature is bilateral granulomatous panuveitis, which is detected on ophthalmologic examination ...
Samiya Al Hashmi, Nasra Al Habsi, Safiya Al Abrawi   +2 more
doaj   +1 more source

Vogt Koyanagi Harada syndrome in a 15-year-old girl, steroids side effects and recurrences

The Turkish Journal of Pediatrics, 2021
Background. Vogt-Koyanagi-Harada Syndrome is rare in childhood and is usually seen between the 2nd and 5th decades. We present a 15-year-old girl with findings of incomplete Vogt-Koyanagi-Harada Syndrome. Case.
Gamze Yıldırım, Cemal Çavdarlı, Emine Yıldız Özdemir, Mehmet Numan Alp   +3 more
doaj   +1 more source

Azathioprine Induced Pancytopenia in a Patient with Vogt-Koyanagi-Harada Disease: A Case Report

Journal of Nepal Medical Association, 2022
Vogt-Koyanagi-Harada disease is a multisystem autoimmune inflammatory disorder that affects the eyes, ears, skin, and the nervous system. It is a rare disease that mainly affects Asian, Hispanic, and Middle Eastern populations.
Sagun Khatri, Saugat Khatri, Sachit Regmi, Sulav Pyakurel, Sanjeet Bhattarai, Pankaj Barman, Dilasha Manandhar, Abhi Kumar Singh   +7 more
doaj   +1 more source

A de novo missense mutation in MPP2 confers an increased risk of Vogt–Koyanagi–Harada disease as shown by trio-based whole-exome sequencing

Cellular & Molecular Immunology, 2023
Vogt–Koyanagi–Harada (VKH) disease is a leading cause of blindness in young and middle-aged people. However, the etiology of VKH disease remains unclear. Here, we performed the first trio-based whole-exome sequencing study, which enrolled 25 VKH patients
Xianyang Liu, Jiayu Meng, Xingyun Liao, Yusen Liu, Qian Zhou, Zongren Xu, Shuming Yin, Q. Cao, Guan-Nan Su, Siyuan He, Wanqian Li, Xiaotang Wang, Guoqing Wang, Dali Li, Peizeng Yang, Shengping Hou   +15 more
semanticscholar   +1 more source

Immunosuppressive therapy for Vogt-Koyanagi-Harada disease: a retrospective study and review of literature

Journal of Ophthalmic Inflammation and Infection, 2023
Background Vogt-Koyanagi-Harada (VKH) disease is an idiopathic autoimmune disease which targets melanin-containing tissues such as the uvea, meninges, ear and skin. This typically presents in the eye with acute findings of granulomatous anterior uveitis,
Najiha Rahman, J. Artiaga, K. Bouras, J. Luis, A. Rees, M. Westcott   +5 more
semanticscholar   +1 more source

A case presentation of an IgA nephropathy patient with Vogt-Koyanagi-Harada syndrome

BMC Nephrology, 2020
Background Vogt-Koyanagi-Harada syndrome is a rare disease characterized by skin and eyelash bleaching, chronic granulomatous iridocyclitis and exudative retinal detachment, and aseptic meningitis and encephalopathy.
Quan Zhang, Xing Fan, Meng Tian, Hongling Han   +3 more
doaj   +1 more source

HLA-DRB1*04:05 is involved in the development of Vogt–Koyanagi–Harada disease-like immune-related adverse events in patients receiving immune checkpoint inhibitors

Scientific Reports, 2023
Immune checkpoint inhibitors (ICIs) activate anti-tumor activity by inhibiting immune checkpoint molecules that suppress inflammatory T-cell activity. However, ICIs can initiate excessive immune responses, thereby causing immune-related adverse events ...
M. Takeuchi, A. Meguro, J. Nakamura, Rei Chikagawa, Raiga Osada, E. Shibuya, Yukiko Hasumi, Norihiro Yamada, M. Ishihara, N. Mizuki   +9 more
semanticscholar   +1 more source

Autoimmune uveitis in Behçet's disease and Vogt‐Koyanagi‐Harada disease differ in tissue immune infiltration and T cell clonality

Clinical & Translational Immunology, 2023
Non‐infectious uveitis is often secondary to systemic autoimmune diseases, with Behçet's disease (BD) and Vogt‐Koyanagi‐Harada disease (VKHD) as the two most common causes.
Hao Kang, Hong-Jian Sun, Yang Yang, Z. Tuong, Ming-Lei Shu, Yun-Bo Wei, Yu Zhang, Di Yu, Yong Tao   +8 more
semanticscholar   +1 more source

Chromatin accessibility analysis reveals regulatory dynamics and therapeutic relevance of Vogt-Koyanagi-Harada disease

Communications Biology, 2022
Single-cell RNA-sequencing and chromatin accessibility analysis reveal transcriptomic and epigenomic changes between healthy patients and those affected by the systemic autoimmune disorder Vogt-Koyanagi-Harada disease.
Wen Shi, Jinguo Ye, Zhuoxing Shi, Caineng Pan, Qikai Zhang, Yuheng Lin, Yuanting Luo, Wenru Su, Yingfeng Zheng, Yizhi Liu   +9 more
doaj   +1 more source

Hints from the skin beneath: Vitiligo in Vogt–Koyanagi–Harada disease

Dermatologica Sinica, 2022
Vogt–Koyanagi–Harada disease (VKHD) is a major vision-threatening autoimmune disease. One of its associated features is vitiligo. Little study has been done on the association between vitiligo and the disease activity of VKHD.
Jo Anne Lim, Wooi Chiang Tan, Norazirah Md Nor   +2 more
doaj   +1 more source