Results 91 to 100 of about 1,848,238 (382)

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

BI-LAYER HYBRID BIOCOMPOSITES: CHEMICAL RESISTANT AND PHYSICAL PROPERTIES

BioResources, 2012
Bi-layer hybrid biocomposites were fabricated by hand lay-up technique by reinforcing oil palm empty fruit bunch (EFB) and jute fibre mats with epoxy matrix. Hybrid composites were prepared by varying the relative weight fraction of the two fibres.
Mohammad Jawaid,, H. P. S. Abdul Khalil,, Azman Hassan,, Elgorban Abdallah   +3 more
doaj  

High Temperature VARTM of Phenylethynyl Terminated Imides (PETI) Resins [PDF]

, 2010
Fabrication of composite structures using vacuum assisted resin transfer molding (VARTM) is generally more affordable than conventional autoclave techniques. Recent efforts have focused on adapting VARTM for the fabrication of high temperature composites.
Britton, Sean M., Cano, Roberto J., Connell, John W., Ghose, Sayata, Jensen, Brian J., Watson, Kent A.   +5 more
core   +1 more source

STRUCTURAL METHODS FOR COMPOSITES IN THE PRESENCE OF POROSITY/VOIDS

, 2013
Porosity/void locations and shapes obtained by X-Ray Computed Tomography are essential for accurate predictions of strength and fatigue life by structural analysis models of curved-beam ...
Guillaume Seon, Yuri G Nikishkov, Andrew Makeev   +2 more
openaire   +2 more sources

Influence of voids on the flexural resistance of the NCF/RTM6 composites

Procedia Engineering, 2011
AbstractA major difficulty to achieve maximum weight savings in the manufacture of composite structural components, is the tendency of these materials have the formation of voids and cracks in the interior and surface components. In aeronautical applications, controlling the volume fraction of fibers, resins and empty the components of composite is ...
T. G. Cruz, T. G. Cruz, Herman Jacobus Cornelis Woorwald, Sérgio Roberto Montoro, Maria Odila Hilário Cioffi, Marcos Yutaka Shiino   +5 more
openaire   +2 more sources

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Development of an impact- and solvent-resistant thermoplastic composite matrix, phase 3 [PDF]

The polyimide from BTDA 1,6-hexanediamine and m-phenylenediamine was selected from a prior study for the present study. Methods to prepare prepreg which would provide low void composites at low molding pressures from the thermoplastic polyimide were ...
Delano, C. B., Kiskiras, C. J.
core   +1 more source

Variable cavity volume tooling for high-performance resin infusion moulding [PDF]

, 2010
This article describes the research carried out by Warwick under the BAE Systems/EPSRC programme ‘Flapless Aerial Vehicles Integrated Interdisciplinary Research – FLAVIIR’.
Achim V., Armstrong D. L., Chowdhury F. H., G J Gibbons, Gibbons G. J., Grande J., J J Segui-Garza, McConnell V. P., R G Hansell, Schwartz M. M., Sutton G., Toi Y.   +11 more
core   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Evaluation of Antibiotic-Releasing Triphasic Bone Void Filler In-Vitro

Journal of Functional Biomaterials, 2018
Bone void fillers (BVFs) containing calcium sulfate, tricalcium phosphate (TCP), and hydroxyapatite can be loaded with antibiotics for infection treatment or prevention under surgeon-directed use.
Michael Harris, Hamza Ahmed, Leslie Pace, Jon Minter, Michael Neel, Jessica Jennings   +5 more
doaj   +1 more source