Results 81 to 90 of about 1,439,477 (352)

Recent trends, technical concepts and components of computer-assisted orthopedic surgery systems: A comprehensive review [PDF]

open access: yes, 2019
Computer-assisted orthopedic surgery (CAOS) systems have become one of the most important and challenging types of system in clinical orthopedics, as they enable precise treatment of musculoskeletal diseases, employing modern clinical navigation systems ...
Kalová, Martina   +5 more
core   +1 more source

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

open access: yesAdvanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng   +12 more
wiley   +1 more source

Volar Fixation of Dorsally Displaced Distal Radial Fracture Using Locking Compression Plate

open access: yesJournal of Orthopaedic Surgery, 2005
Purpose. To evaluate the functional and radiological results of treating unstable fractures of the dorsal distal radius with a volar locking plate. Methods.
KK Wong, KW Chan, TK Kwok, KH Mak
doaj   +1 more source

Corrective Osteotomy with Volar and Dorsal Fixation for Malunion of Intra‐Articular Fracture of the Distal Radius: A Retrospective Study

open access: yesOrthopaedic Surgery, 2022
Objectives Although corrective osteotomy with volar or dorsal plate fixation can treat malunion of distal radius fractures, each has its own disadvantages.
Huihao Zhang   +12 more
doaj   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan   +11 more
wiley   +1 more source

Radiographic Outcomes of Dorsal Spanning Plate for Treatment of Comminuted Distal Radius Fractures in Non-Elderly Patients

open access: yesJournal of Hand Surgery Global Online, 2020
Purpose: Multifragmentary fractures of the distal radius with articular and metaphyseal comminution (AO 23-C3) represent challenging injuries to manage.
Behnam Sharareh, MD, Scott Mitchell, MD
doaj   +1 more source

Dislocation of the metacarpophalangeal joint of the index finger requiring open reduction due to the presence of an intra-articular sesamoid bone

open access: yesSAGE Open Medical Case Reports, 2021
Complex dislocation of the metacarpophalangeal joint of the index finger is rare and often requires surgical intervention. Here, we present a case of an index finger metacarpophalangeal joint dislocation requiring open reduction due to obstruction by a ...
Elizabeth S O’Neill   +4 more
doaj   +1 more source

In vitro inhibitory effect of selected fungicides on mycelial growth of ambrosia fungus associated with the black coffee twig borer, Xylosandrus compactus Eichhoff (Coleoptera: Curculionidae) in Uganda [PDF]

open access: yes, 2015
Black coffee twig borer is a new but rapidly spreading insect pest of coffee in Uganda. Female beetles bore into primary branches/twigs and cultivate an ambrosia fungus for feeding their larvae.
Kagezi, Godfrey   +6 more
core   +1 more source

Volar plating in DRF with an intact volar cortex

open access: yes, 2020
Can you do an adequate stable fixation of a dorsally displaced intra-articular impacted fracture with an intact or non-displaced volar cortex?
A. Fernández, J. Jupiter
openaire   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

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