Mechanistic insights into volatile anesthetic modulation of K2P channels [PDF]
eLife, 2020 K2P potassium channels are known to be modulated by volatile anesthetic (VA) drugs and play important roles in clinically relevant effects that accompany general anesthesia.
Aboubacar Wague +9 more
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Comparison of volatile anesthetic-induced preconditioning in cardiac and cerebral system: molecular mechanisms and clinical aspects [PDF]
European Journal of Medical Research, 2018 Volatile anesthetic-induced preconditioning (APC) has shown to have cardiac and cerebral protective properties in both pre-clinical models and clinical trials.
Shasha Chen +3 more
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Cancerous phenotypes associated with hypoxia-inducible factors are not influenced by the volatile anesthetic isoflurane in renal cell carcinoma. [PDF]
PLoS ONE, 2019 The possibility that anesthesia during cancer surgery may affect cancer recurrence, metastasis, and patient prognosis has become one of the most important topics of interest in cancer treatment.
Chisato Sumi +7 more
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The neuroendocrine stress response compensates for suppression of insulin secretion by volatile anesthetic agents: An observational study [PDF]
Physiological Reports, 2023 Alterations in perioperative metabolic function, particularly hyperglycemia, are associated with increased post‐operative complications, even in patients without preexisting metabolic abnormalities.
William G. Tharp +4 more
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Sodium channels as targets for volatile anesthetics [PDF]
Frontiers in Pharmacology, 2012 The molecular mechanisms of modern inhaled anesthetics although widely used in clinical settings are still poorly understood. Considerable evidence supports effects on membrane proteins such as ligand- and voltage-gated ion channels of excitable cells ...
Karl F. Herold, Hugh C. Hemmings
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Age and Solubility of Volatile Anesthetics in Blood [PDF]
Anesthesiology, 1984 The more rapid rate of rise of alveolar anesthetic partial pressure in children compared with adults may be explained in part by an increasing solubility of volatile anesthetics in blood with age. To investigate this possibility, the authors measured the blood-gas partition coefficients of isoflurane, enflurane, halothane, and methoxyflurane in four ...
Jerrold Lerman +2 more
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The effects of end-tidal controlled low-flow anesthesia on anesthetic agent consumption in elective surgeries: randomized controlled trial [PDF]
BMC AnesthesiologyPurpose The environmental impact and cost of volatile anesthetics are significant concerns in modern anesthesia. Automated end-tidal control systems aim to optimize anesthetic delivery by reducing waste and improving efficiency.
Elzem Sen +6 more
doaj +2 more sources
Use of remimazolam as an adjunct to general anesthesia for an adolescent with MELAS syndrome. [PDF]
Pediatric Anesthesia and Critical Care Journal (PACCJ), 2022 MELAS syndrome is an acronym so named because of the characteristic clinical and pathophysiologic features including mitochondrial encephalo-myopathy, lactic aci- dosis, and stroke-like episodes.
N. Gyurgyik +3 more
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Frontiers in Cardiovascular Medicine, 2023 BackgroundStudies investigating the cardioprotective effect of volatile anesthetics on cardiac troponins in off-pump coronary artery bypass grafting (OPCAB) surgery remain controversial.
Chenghong Zhang +6 more
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Volatile Anesthetics and Immunity [PDF]
Immunological Investigations, 2017 Historically, volatile anesthetics have demonstrated interesting interactions with both the innate and adaptive immune systems. This review organizes these interactions into four phases: recognition, recruitment, response, and resolution. These phases represent a range of proinflammatory, inflammatory, and innate and adaptive immune regulatory ...
Paul R. Knight +3 more
openaire +3 more sources