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Volatile Anesthetics Depress Spinal Motor Neurons
Anesthesiology, 1996Background Depression of spinal alpha-motor neurons apparently plays a role in the surgical immobility induced by isoflurane. Using the noninvasive technique of F-wave analysis, the authors tested the hypothesis that depressed motor neuron excitability is an effect common to other clinically relevant inhaled anesthetics.
I J, Rampil, B S, King
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Volatile Anesthetics and Neuroprotection
2015Since 1963, many studies have demonstrated the protective and preconditioning effects of volatile anesthetics on cerebral ischemia, and it has also been suggested that they can delay neuronal cell death, especially in the developing brain. Various molecular mechanisms involving the numerous pathways of the neuronal cell death cascade have been reported
Yasunori Mishima, Kazuo Ushijima
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Volatile anesthetic effects on ischemic myocardium
Current Opinion in Anaesthesiology, 1998Volatile anesthetics, particularly the new generation of agents, have a very rapid onset and offset of action. These properties allow for quick recovery from clinical anesthesia. Because there is additional evidence that these agents have protective effects during myocardial ischemia, there may be advantages for 'fast tracking' patients undergoing ...
N, Nader-Djalal, P R, Knight
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Anesthesiology Clinics of North America, 1993
Summary In conclusion, the physiologic response to desflurane, for the most part, closely mimics the response to isoflurane. In the steady state, it is difficult to distinguish these two drugs on the basis of their effect on the central and regional hemodynamics, as well as on pulmonary function.
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Summary In conclusion, the physiologic response to desflurane, for the most part, closely mimics the response to isoflurane. In the steady state, it is difficult to distinguish these two drugs on the basis of their effect on the central and regional hemodynamics, as well as on pulmonary function.
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Volatile anesthetics and mucociliary clearance.
Minerva anestesiologica, 2008The aim of this prospective, randomized, double blind study was to evaluate the possible modification of in vivo nasal mucociliary clearance by three different volatile agents: sevoflurane, isoflurane and desflurane, following intravenous induction and tracheal intubation.Following institutional approval and informed consent, 60 patients scheduled for ...
Kutluhan, AHMET +5 more
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Volatile Anesthetics Reduce Mortality in Cardiac Surgery
Journal of Cardiothoracic and Vascular Anesthesia, 2009A recent meta-analysis suggested that volatile anesthetics reduce postoperative mortality after cardiac surgery. Nonetheless, whether volatile anesthetics improve the outcome of cardiac surgical patients is still a matter of debate. The authors investigated whether the use of volatile anesthetics reduces mortality in cardiac surgery.
BIGNAMI E +7 more
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Cardioprotection with Volatile Anesthetics in Cardiac Surgery
Asian Cardiovascular and Thoracic Annals, 2008Myocardial ischemia during the perioperative period is a major cause of morbidity and mortality after surgery. Experimental data indicate that clinical concentrations of volatile anesthetics protect the myocardium from ischemia and reperfusion injury, as shown by decreased infarct size and more rapid postoperative recovery of contractile function ...
Lorsomradee, Suraphong +3 more
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Volatile Anesthetics and Coronary Collateral Circulation
1994Publisher Summary In this chapter, a study demonstrates that isoflurane and a new volatile anesthetic, sevoflurane, do not abnormally redistribute collateral blood flow away from an area distal to a total coronary artery occlusion. Vasodilation in the region supplied by the stenotic artey causes a decrease in coronary artery pressure distal to the ...
J R, Kersten +3 more
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Cardioprotection with volatile anesthetics: clinical relevance
Current Opinion in Anaesthesiology, 2004Increasing experimental evidence is indicating that volatile anesthetic agents may exert direct cardioprotective effects. They have been shown to directly precondition or indirectly enhance ischemic preconditioning. This results in protection against reversible and irreversible ischemic myocardial damage. In addition, volatile anesthetics also decrease
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