Results 171 to 180 of about 824,803 (284)
Small Airways Dysfunction and Remission in Adults With Asthma: A Longitudinal Exploratory Analysis of the AssessmenT of smalL Airways involvemeNT In aSthma (ATLANTIS) Study
Allergy, EarlyView.We conducted a post hoc analysis of ATLANTIS, a multinational prospective study including 684 adults with asthma. Fewer small airway symptoms and lower disease activity are independently associated with asthma remission. Replicated airway transcriptomic signatures show increased IL‐4/13 signalling and reduced coagulation pathways across the ATLANTIS ...Akshi Kumar, Rory Chan, Nazanin Zounemat‐Kermani, Eleanor Quek, Ian M. Adcock, Bianca Beghe, Christopher Brightling, Dave Singh, Janwillem Kocks, Alberto Papi, Klaus F. Rabe, Ulrica Scaffidi‐Argentina, Maarten van den Berge, Monica Kraft, Salman Siddiqui +14 morewiley +1 more sourceDistinct Gene Expression Profiles of Ara h 2‐Specific B Cells in Desensitization and Tolerance During Peanut Oral Immunotherapy
Allergy, EarlyView.Gene expression of Ara h 2‐specific B cells over the course of the peanut OIT. Isotype of allergen‐specific B cells changes through OIT towards IgG4. Peanut OIT changes the gene expression of allergen‐specific memory B cells. OIT patients showed increased gene expression for regulatory B cells and immune regulation.Stephan R. Schneider, Juan‐Felipe López, Huseyn Babayev, Willem van de Veen, Minglin Yang, Cezmi A. Akdis, Kari Nadeau, Carolyn H. Baloh, Stacie M. Jones, Lisa M. Wheatley, Mübeccel Akdis, IMPACT, Amy M. Scurlock, D. Pesek, Joy Laurienzo‐Panza, Marshall Plaut, A. Wesley Burks, Edwin H. Kim, Mike Kulis, Anna Nowak‐Wegrzyn, Hugh A. Sampson, Julie Wang, Robert A. Wood, Sharon Chinthrajah, Robert Sayantani B. Sindher, Jacqueline Johnson, Katharine Spain, Denise C. Babineau, Hyunsook Chin, Rachel Yan, Don Whitehouse, Michelle L. Sever, Srinath Sanda, David Larson, Tielin Qin, Gina Marchesini, Kavitha Gilroy, Sylvia Posso, Sabrina Skiba, Thien‐Son Nguyen, Adam Wojno, Tuan Nguyen, Vivian Gersuk, Quynh‐Anh Nguyen, Jessica Garber, Kimberly O'Brien, Brandon Larson, C. Cousens‐Jacobs, Alex Hu +48 morewiley +1 more sourceCommon Food Emulsifiers Impair Epithelial Barrier Integrity and Trigger Pro‐Inflammatory Responses and IgE Production
Allergy, EarlyView.Soy lecithin and DATEM, the two commonly used food emulsifiers introduced into many foods including peanut butter and puffed bread, in the 2000s, impair intestinal epithelial barrier integrity in human gut‐on‐a‐chip and induced pluripotent stem cell colon organoid models.Duygu Yazici, Yuka Hayashi, Yagiz Pat, Jennifer Hotie, Mehmet Ali Balci, Sena Ardicli, Juan Felipe Lopez, Ozge Ardicli, Bingjie Zhao, Angel Maldonado, Can Zeyneloglu, Kenji Matsumoto, Manru Li, Beate Rückhert, Lihong Chang, Ismail Ogulur, Vahap Eldem, Raja Dhir, Mubeccel Akdis, Kari Nadeau, Oscar Palomares, Hideaki Morita, Cezmi A. Akdis +22 morewiley +1 more sourceMineralized carbonates contribute to the millennial durability of Roman concrete. [PDF]
Sci AdvZhu X, Chae SR, McElhany S, Liang C, Zheng Q, Li J, Fondi V, Del Ferro S, Modena Altieri A, Lisabeth HP, Bhattacharjee A, Fouke BW, Wenk HR, Monteiro PJM. +13 moreeuropepmc +1 more sourceSoil wetting and drying processes influence stone artefact distribution in clay‐rich soils: A case study from Middle Gidley Island in Murujuga, northwest Western Australia
Archaeometry, EarlyView.Abstract
Soils that contain swelling clay minerals (e.g., montmorillonite) expand and contract during wetting and drying, causing movement within the soil profile. This process, known as argilliturbation, can alter artefact distributions, destroy stratigraphy and complicate the interpretation of archaeological deposits.Caroline Mather, Matthias Leopold, Kaitlin Sullivan, Kane Ditchfield, Tom Horrocks, Luke Gliganic, Emma Beckett, Diana Patalwala, Emielda Yusiharni, Michael Smirk, William Hiscock, Jo McDonald +11 morewiley +1 more sourceGlobal groundwater contamination by geogenic fluoride. [PDF]
Environ Geochem HealthAli S, Mishra P, Brindha K, Gutiérrez M, Kumar R, Sunkari ED, Gevera PK, Karro E, Egbueri JC, Dehbandi R, Chandrajith R, Li P, Islam ARMT, Yun ST, Sabino H, Emilio MD, Baba A, Durrani TS, Amiri V, Aqeel A, Ijumulana J, Edokpayi JN, Schafer D, Razowska-Jaworek L, Alarcón-Herrera MT, Batdelger O, Goswami R, Farooqi A, Fabio AE, Recepoğlu YK, Paz-Montelongo S, Bhattacharya P. +31 moreeuropepmc +1 more source
