Results 211 to 220 of about 26,348 (308)

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

open access: yesThe FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia   +7 more
wiley   +1 more source

Mechanical stiffness orchestrates distinct regulation of MRTFs and YAP/TAZ transcriptional cofactors in hepatocytes

open access: yesThe FEBS Journal, EarlyView.
MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz   +13 more
wiley   +1 more source

Resolving Micrometre‐Scale Zircon Growth in Silicic Systems by 7 μm LA‐MC‐ICP‐MS U‐Pb Dating: Linking Petrology and Geochronology in Silicic Volcanic and Granitic Rocks from Victoria, Australia

open access: yesGeostandards and Geoanalytical Research, EarlyView.
Key Points 7 μm spot‐diameter LA‐MC‐ICP‐MS analyses yield accurate zircon U‐Pb ages. 1013 Ω amplifier resistors improve low‐signal Pb measurements. Saturn correction protocols minimise down‐hole fractionation effects. We present a systematic evaluation of high spatial‐resolution zircon U‐Pb dating using a Thermo Scientific Neoma multi‐collector ICP‐MS ...
Cristiano Lana, John D. Clemens
wiley   +1 more source

Imaging Point Source Groundwater Discharges in a Confined Coastal Aquifer Using Electrical Resistivity

open access: yesGroundwater, EarlyView.
Marine electrical resistivity tomography (ERT) is applied to characterize point‐source submarine groundwater discharge (PSGD) along NW Yucatán. ERT observations and forward modeling constrain conduit detectability under varying hydrogeological conditions.
Mariana Gómez‐Nicolás   +6 more
wiley   +1 more source

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