Results 271 to 280 of about 868,198 (351)

In vivo modeling of lethal congenital contracture syndrome 1 suggests pathomechanisms in cellular stress responses

open access: yesThe FEBS Journal, EarlyView.
Gle1 knockout mice fail to segregate cell lineages at the blastocyst stage, resulting in very early embryonic lethality. Gle1 knock‐in (KI) mice harboring a pathogenic variant giving rise to lethal congenital contracture syndrome 1 show both known and novel innervation defects, supportive of multiorgan pathology in human fetuses.
Tomáš Zárybnický   +22 more
wiley   +1 more source

Synthetic trap‐peptides identify a TOM complex phosphatase – PP2A dephosphorylates Tom6

open access: yesThe FEBS Journal, EarlyView.
Synthetic trap‐peptides facilitate the identification of complete holoenzymes that bind to the target sequence remarkably close to the phosphorylation site. PP4 bound to, but did not dephosphorylate, the peptide substrate taken from yeast Tom6 pSer16, showing that proximity alone does not induce phosphatase activity.
Laura Scheinost   +7 more
wiley   +1 more source

A database for igneous rocks of the Newfoundland Appalachians. [PDF]

open access: yesSci Data
Wang C   +6 more
europepmc   +1 more source

Individuality obscures geographical song variation in two passerine sister species with contrasting distributions and movement ecology

open access: yesIbis, EarlyView.
Songbirds are a well‐established model group for the study of cultural evolution as their songs are learned (i.e. culturally transmitted), which may lead to divergence in song characteristics between populations. Song variation across populations may be affected by geographical isolation, timing and duration of the learning period, and life strategies ...
Javier Oñate‐Casado   +8 more
wiley   +1 more source

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