Results 121 to 130 of about 257,872 (307)

Strong seismic reflections indicating possible eruptible magma beneath the Tatun Volcano Group in Taiwan

open access: yesScientific Reports
The Tatun Volcano Group (TVG), located at the northern tip of Taiwan, is situated near the Taipei metropolitan area. A future eruption of the TVG could have a significant impact not only on Taipei but also on the global economy, as Taiwan produces over ...
Cheng-Horng Lin   +2 more
doaj   +1 more source

Thymosin Alpha‐1 Provides Direct Neuroprotection by Engaging the Orexin Receptor HCRTR1 to Suppress Neuronal Necroptosis

open access: yesAdvanced Science, EarlyView.
In this study, we unveil a thymus‐brain endocrine axis wherein Tα1 engages HCRTR1 to inhibit RIPK3‐mediated necroptosis. This study nominates the Tal‐HCRTR1‐RIPK3 axis as a potent and clinically translatable therapeutic target for stroke and neurodegeneration.
Xinmei Kang   +11 more
wiley   +1 more source

Cascades Volcano Observatory - Learn About Volcanoes: Frequently Asked Volcano Questions

open access: yes
This page provides the answers to frequently asked questions about volcanoes. It is created by the United States Geological Survey. Topics addressed include: What Is A Volcano? Why Do Volcanoes Occur? How Do Volcanoes Erupt?

core  

A scanning electron microscope-energy dispersive spectrometry (SEM-EDS) method for the quantitative analysis of common volcanic phases

open access: yesVolcanica
In situ microanalysis by X-ray spectrometry is a fundamental geochemical technique for volcanology and the geosciences generally and typically performed using an electron microprobe (EPMA) equipped with wavelength dispersive spectrometers (WDS).
Nathan L Andersen, Heather Winslow
doaj   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li   +15 more
wiley   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu   +13 more
wiley   +1 more source

Mitigation of human cognitive bias in volcanic eruption forecasting

open access: yesJournal of Applied Volcanology
Modern operational eruption forecasting methods rely heavily on human judgment in the face of uncertainty and are thus susceptible to myriad cognitive biases and errors by the scientist-forecasters.
Heather M. N. Wright   +2 more
doaj   +1 more source

Biofilm‐Binding Phages Enhance Biofilm Eradication by Synergistic Photothermal and Photodynamic Therapy

open access: yesAdvanced Science, EarlyView.
Engineered phage‐based trifunctional nanofibers are developed for synergistic biofilm eradication. Biofilm‐binding phages, armed with AuNPs and TCPP, serve as both warheads and scaffolds, endowing the phototherapy agents with biofilm‐anchoring ability. Upon light irradiation, AuNPs induce photothermal therapy, while TCPP generates 1O2 for photodynamic ...
Ying Cao   +9 more
wiley   +1 more source

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